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MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products.
Bioorg Med Chem Lett. 1998 Oct 20;8(20):2839-44. doi: 10.1016/s0960-894x(98)00522-8.
Bioorg Med Chem Lett. 1998.
PMID: 9873633
Beyond U0126. Dianion chemistry leading to the rapid synthesis of a series of potent MEK inhibitors.
Wityak J, Hobbs FW, Gardner DS, Santella JB 3rd, Petraitis JJ, Sun JH, Favata MF, Daulerio AJ, Horiuchi KY, Copeland RA, Scherle PA, Jaffe BD, Trzaskos JM, Magolda RL, Trainor GL, Duncia JV.
Wityak J, et al. Among authors: daulerio aj.
Bioorg Med Chem Lett. 2004 Mar 22;14(6):1483-6. doi: 10.1016/j.bmcl.2004.01.012.
Bioorg Med Chem Lett. 2004.
PMID: 15006386
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Identification of a novel inhibitor of mitogen-activated protein kinase kinase.
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM.
Favata MF, et al. Among authors: daulerio aj.
J Biol Chem. 1998 Jul 17;273(29):18623-32. doi: 10.1074/jbc.273.29.18623.
J Biol Chem. 1998.
PMID: 9660836
Free article.
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Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes.
Scherle PA, Jones EA, Favata MF, Daulerio AJ, Covington MB, Nurnberg SA, Magolda RL, Trzaskos JM.
Scherle PA, et al. Among authors: daulerio aj.
J Immunol. 1998 Nov 15;161(10):5681-6.
J Immunol. 1998.
PMID: 9820549
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An ELISA assay for murine interleukin-1 beta.
Newton RC, Dowling R, Daulerio AJ, Culp S.
Newton RC, et al. Among authors: daulerio aj.
J Immunol Methods. 1993 May 26;161(2):257-64. doi: 10.1016/0022-1759(93)90301-m.
J Immunol Methods. 1993.
PMID: 8505554
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