Wexler RR - Search Results

1

MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products.

Duncia JV, Santella JB 3rd, Higley CA, Pitts WJ, Wityak J, Frietze WE, Rankin FW, Sun JH, Earl RA, Tabaka AC, Teleha CA, Blom KF, Favata MF, Manos EJ, Daulerio AJ, Stradley DA, Horiuchi K, Copeland RA, Scherle PA, Trzaskos JM, Magolda RL, Trainor GL, Wexler RR, Hobbs FW, Olson RE. Duncia JV, et al. Among authors: wexler rr. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2839-44. doi: 10.1016/s0960-894x(98)00522-8. Bioorg Med Chem Lett. 1998. PMID: 9873633

2

Rationale for the chemical development of angiotensin II receptor antagonists.

Wexler RR, Carini DJ, Duncia JV, Johnson AL, Wells GJ, Chiu AT, Wong PC, Timmermans PB. Wexler RR, et al. Am J Hypertens. 1992 Dec;5(12 Pt 2):209S-220S. doi: 10.1093/ajh/5.12.209s. Am J Hypertens. 1992. PMID: 1290616 Review.

3

The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist.

Duncia JV, Carini DJ, Chiu AT, Johnson AL, Price WA, Wong PC, Wexler RR, Timmermans PB. Duncia JV, et al. Among authors: wexler rr. Med Res Rev. 1992 Mar;12(2):149-91. doi: 10.1002/med.2610120203. Med Res Rev. 1992. PMID: 1619965 Review. No abstract available.

4

The discovery of a new class of highly specific nonpeptide angiotensin II receptor antagonists.

Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Johnson AL, Wexler RR. Timmermans PB, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):275S-281S. doi: 10.1093/ajh/4.4.275s. Am J Hypertens. 1991. PMID: 1854452 Review.

5

In vitro pharmacology of DuP 753.

Chiu AT, McCall DE, Price WA Jr, Wong PC, Carini DJ, Duncia JV, Wexler RR, Yoo SE, Johnson AL, Timmermans PB. Chiu AT, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):282S-287S. doi: 10.1093/ajh/4.4.282s. Am J Hypertens. 1991. PMID: 1854453 Review.

6

In vivo pharmacology of DuP 753.

Wong PC, Price WA Jr, Chiu AT, Duncia JV, Carini DJ, Wexler RR, Johnson AL, Timmermans PB. Wong PC, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):288S-298S. doi: 10.1093/ajh/4.4.288s. Am J Hypertens. 1991. PMID: 1854454 Review.

7

Angiotensin II receptor heterogeneity.

Herblin WF, Chiu AT, McCall DE, Ardecky RJ, Carini DJ, Duncia JV, Pease LJ, Wong PC, Wexler RR, Johnson AL, et al. Herblin WF, et al. Among authors: wexler rr. Am J Hypertens. 1991 Apr;4(4 Pt 2):299S-302S. doi: 10.1093/ajh/4.4.299s. Am J Hypertens. 1991. PMID: 1854455

8

Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives.

Carini DJ, Duncia JV, Aldrich PE, Chiu AT, Johnson AL, Pierce ME, Price WA, Santella JB 3rd, Wells GJ, Wexler RR, et al. Carini DJ, et al. Among authors: wexler rr. J Med Chem. 1991 Aug;34(8):2525-47. doi: 10.1021/jm00112a031. J Med Chem. 1991. PMID: 1875348

9

Angiotensin II receptor antagonists. From discovery to antihypertensive drugs.

Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Wexler RR, Johnson AL. Timmermans PB, et al. Among authors: wexler rr. Hypertension. 1991 Nov;18(5 Suppl):III136-42. doi: 10.1161/01.hyp.18.5_suppl.iii136. Hypertension. 1991. PMID: 1937677 Review.

10

Nonpeptide angiotensin II receptor antagonists: a novel class of antihypertensive agents.

Timmermans PB, Carini DJ, Chiu AT, Duncia JV, Price WA Jr, Wells GJ, Wong PC, Wexler RR, Johnson AL. Timmermans PB, et al. Among authors: wexler rr. Blood Vessels. 1990;27(2-5):295-300. doi: 10.1159/000158821. Blood Vessels. 1990. PMID: 1978694 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

194 results

Search Page