Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

48 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products.
Duncia JV, Santella JB 3rd, Higley CA, Pitts WJ, Wityak J, Frietze WE, Rankin FW, Sun JH, Earl RA, Tabaka AC, Teleha CA, Blom KF, Favata MF, Manos EJ, Daulerio AJ, Stradley DA, Horiuchi K, Copeland RA, Scherle PA, Trzaskos JM, Magolda RL, Trainor GL, Wexler RR, Hobbs FW, Olson RE. Duncia JV, et al. Among authors: wityak j. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2839-44. doi: 10.1016/s0960-894x(98)00522-8. Bioorg Med Chem Lett. 1998. PMID: 9873633
Discovery of an orally active series of isoxazoline glycoprotein IIb/IIIa antagonists.
Xue CB, Wityak J, Sielecki TM, Pinto DJ, Batt DG, Cain GA, Sworin M, Rockwell AL, Roderick JJ, Wang S, Orwat MJ, Frietze WE, Bostrom LL, Liu J, Higley CA, Rankin FW, Tobin AE, Emmett G, Lalka GK, Sze JY, Di Meo SV, Mousa SA, Thoolen MJ, Racanelli AL, Olson RE, et al. Xue CB, et al. Among authors: wityak j. J Med Chem. 1997 Jun 20;40(13):2064-84. doi: 10.1021/jm960799i. J Med Chem. 1997. PMID: 9207948
Orally active isoxazoline glycoprotein IIb/IIIa antagonists with extended duration of action.
Olson RE, Sielecki TM, Wityak J, Pinto DJ, Batt DG, Frietze WE, Liu J, Tobin AE, Orwat MJ, Di Meo SV, Houghton GC, Lalka GK, Mousa SA, Racanelli AL, Hausner EA, Kapil RP, Rabel SR, Thoolen MJ, Reilly TM, Anderson PS, Wexler RR. Olson RE, et al. Among authors: wityak j. J Med Chem. 1999 Apr 8;42(7):1178-92. doi: 10.1021/jm980348t. J Med Chem. 1999. PMID: 10197962
Isoxazolines as potent antagonists of the integrin alpha(v)beta(3).
Pitts WJ, Wityak J, Smallheer JM, Tobin AE, Jetter JW, Buynitsky JS, Harlow PP, Solomon KA, Corjay MH, Mousa SA, Wexler RR, Jadhav PK. Pitts WJ, et al. Among authors: wityak j. J Med Chem. 2000 Jan 13;43(1):27-40. doi: 10.1021/jm9900321. J Med Chem. 2000. PMID: 10633036
Oral antiplatelet efficacy and specificity of a novel nonpeptide platelet GPIIb/IIIa receptor antagonist, DMP 802.
Mousa SA, Olson RE, Bozarth JM, Lorelli W, Forsythe MS, Racanelli A, Gibbs S, Schlingman K, Bozarth T, Kapil R, Wityak J, Sielecki TM, Wexler RR, Thoolen MJ, Slee A, Reilly TM, Anderson PS, Friedman PA. Mousa SA, et al. Among authors: wityak j. J Cardiovasc Pharmacol. 1998 Aug;32(2):169-76. doi: 10.1097/00005344-199808000-00001. J Cardiovasc Pharmacol. 1998. PMID: 9700976
48 results