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Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia.
Braga L, Ali H, Secco I, Chiavacci E, Neves G, Goldhill D, Penn R, Jimenez-Guardeño JM, Ortega-Prieto AM, Bussani R, Cannatà A, Rizzari G, Collesi C, Schneider E, Arosio D, Shah AM, Barclay WS, Malim MH, Burrone J, Giacca M. Braga L, et al. Nature. 2021 Jun;594(7861):88-93. doi: 10.1038/s41586-021-03491-6. Epub 2021 Apr 7. Nature. 2021. PMID: 33827113 Free PMC article.
TMPRSS2 promotes SARS-CoV-2 evasion from NCOA7-mediated restriction.
Khan H, Winstone H, Jimenez-Guardeño JM, Graham C, Doores KJ, Goujon C, Matthews DA, Davidson AD, Rihn SJ, Palmarini M, Neil SJD, Malim MH. Khan H, et al. PLoS Pathog. 2021 Nov 22;17(11):e1009820. doi: 10.1371/journal.ppat.1009820. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34807954 Free PMC article.
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation.
Lista MJ, Matos PM, Maguire TJA, Poulton K, Ortiz-Zapater E, Page R, Sertkaya H, Ortega-Prieto AM, Scourfield E, O'Byrne AM, Bouton C, Dickenson RE, Ficarelli M, Jimenez-Guardeño JM, Howard M, Betancor G, Galao RP, Pickering S, Signell AW, Wilson H, Cliff P, Kia Ik MT, Patel A, MacMahon E, Cunningham E, Doores K, Agromayor M, Martin-Serrano J, Perucha E, Mischo HE, Shankar-Hari M, Batra R, Edgeworth J, Zuckerman M, Malim MH, Neil S, Martinez-Nunez RT. Lista MJ, et al. PLoS One. 2021 Sep 15;16(9):e0256813. doi: 10.1371/journal.pone.0256813. eCollection 2021. PLoS One. 2021. PMID: 34525109 Free PMC article.
17 results