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SARS-CoV-2 can recruit a heme metabolite to evade antibody immunity.
Rosa A, Pye VE, Graham C, Muir L, Seow J, Ng KW, Cook NJ, Rees-Spear C, Parker E, Dos Santos MS, Rosadas C, Susana A, Rhys H, Nans A, Masino L, Roustan C, Christodoulou E, Ulferts R, Wrobel AG, Short CE, Fertleman M, Sanders RW, Heaney J, Spyer M, Kjær S, Riddell A, Malim MH, Beale R, MacRae JI, Taylor GP, Nastouli E, van Gils MJ, Rosenthal PB, Pizzato M, McClure MO, Tedder RS, Kassiotis G, McCoy LE, Doores KJ, Cherepanov P. Rosa A, et al. Sci Adv. 2021 May 28;7(22):eabg7607. doi: 10.1126/sciadv.abg7607. Print 2021 May. Sci Adv. 2021. PMID: 33888467 Free PMC article.
The effect of Omicron breakthrough infection and extended BNT162b2 booster dosing on neutralization breadth against SARS-CoV-2 variants of concern.
Graham C, Lechmere T, Rehman A, Seow J, Kurshan A, Huettner I, Maguire TJA, Tam JCH, Cox D, Ward C, Racz M, Waters A, Mant C, Malim MH, Fox J, Doores KJ. Graham C, et al. PLoS Pathog. 2022 Oct 3;18(10):e1010882. doi: 10.1371/journal.ppat.1010882. eCollection 2022 Oct. PLoS Pathog. 2022. PMID: 36191037 Free PMC article.
ChAdOx1 nCoV-19 vaccine elicits monoclonal antibodies with cross-neutralizing activity against SARS-CoV-2 viral variants.
Seow J, Graham C, Hallett SR, Lechmere T, Maguire TJA, Huettner I, Cox D, Khan H, Pickering S, Roberts R, Waters A, Ward CC, Mant C, Pitcher MJ, Spencer J, Fox J, Malim MH, Doores KJ. Seow J, et al. Cell Rep. 2022 May 3;39(5):110757. doi: 10.1016/j.celrep.2022.110757. Epub 2022 Apr 15. Cell Rep. 2022. PMID: 35477023 Free PMC article.