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2021 3
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Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.
Gangoso E, Southgate B, Bradley L, Rus S, Galvez-Cancino F, McGivern N, Güç E, Kapourani CA, Byron A, Ferguson KM, Alfazema N, Morrison G, Grant V, Blin C, Sou I, Marques-Torrejon MA, Conde L, Parrinello S, Herrero J, Beck S, Brandner S, Brennan PM, Bertone P, Pollard JW, Quezada SA, Sproul D, Frame MC, Serrels A, Pollard SM. Gangoso E, et al. Cell. 2021 Apr 29;184(9):2454-2470.e26. doi: 10.1016/j.cell.2021.03.023. Epub 2021 Apr 14. Cell. 2021. PMID: 33857425 Free PMC article.
Glioblastoma cell fate is differentially regulated by the microenvironments of the tumor bulk and infiltrative margin.
Garcia-Diaz C, Pöysti A, Mereu E, Clements MP, Brooks LJ, Galvez-Cancino F, Castillo SP, Tang W, Beattie G, Courtot L, Ruiz S, Roncaroli F, Yuan Y, Marguerat S, Quezada SA, Heyn H, Parrinello S. Garcia-Diaz C, et al. Cell Rep. 2023 May 30;42(5):112472. doi: 10.1016/j.celrep.2023.112472. Epub 2023 May 5. Cell Rep. 2023. PMID: 37149862 Free article.
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Marqués-Torrejón MÁ, Williams CAC, Southgate B, Alfazema N, Clements MP, Garcia-Diaz C, Blin C, Arranz-Emparan N, Fraser J, Gammoh N, Parrinello S, Pollard SM. Marqués-Torrejón MÁ, et al. Nat Commun. 2021 May 10;12(1):2594. doi: 10.1038/s41467-021-22813-w. Nat Commun. 2021. PMID: 33972529 Free PMC article.
The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Nat Commun. 2021 Apr 12;12(1):2184. doi: 10.1038/s41467-021-22225-w. Nat Commun. 2021. PMID: 33846316 Free PMC article.
Injury primes mutation-bearing astrocytes for dedifferentiation in later life.
Simpson Ragdale H, Clements M, Tang W, Deltcheva E, Andreassi C, Lai AG, Chang WH, Pandrea M, Andrew I, Game L, Uddin I, Ellis M, Enver T, Riccio A, Marguerat S, Parrinello S. Simpson Ragdale H, et al. Curr Biol. 2023 Mar 27;33(6):1082-1098.e8. doi: 10.1016/j.cub.2023.02.013. Epub 2023 Feb 24. Curr Biol. 2023. PMID: 36841240 Free PMC article.
Author Correction: The white matter is a pro-differentiative niche for glioblastoma.
Brooks LJ, Clements MP, Burden JJ, Kocher D, Richards L, Devesa SC, Zakka L, Woodberry M, Ellis M, Jaunmuktane Z, Brandner S, Morrison G, Pollard SM, Dirks PB, Marguerat S, Parrinello S. Brooks LJ, et al. Nat Commun. 2022 Apr 14;13(1):2163. doi: 10.1038/s41467-022-29916-y. Nat Commun. 2022. PMID: 35422055 Free PMC article. No abstract available.