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Neuroinvasion and Neurotropism by SARS-CoV-2 Variants in the K18-hACE2 Mouse.
Seehusen F, Clark JJ, Sharma P, Bentley EG, Kirby A, Subramaniam K, Wunderlin-Giuliani S, Hughes GL, Patterson EI, Michael BD, Owen A, Hiscox JA, Stewart JP, Kipar A. Seehusen F, et al. Viruses. 2022 May 11;14(5):1020. doi: 10.3390/v14051020. Viruses. 2022. PMID: 35632761 Free PMC article.
Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers.
Dong X, Penrice-Randal R, Goldswain H, Prince T, Randle N, Donovan-Banfield I, Salguero FJ, Tree J, Vamos E, Nelson C, Clark J, Ryan Y, Stewart JP, Semple MG, Baillie JK, Openshaw PJM, Turtle L, Matthews DA, Carroll MW, Darby AC, Hiscox JA. Dong X, et al. Gigascience. 2022 May 26;11:giac045. doi: 10.1093/gigascience/giac045. Gigascience. 2022. PMID: 35639883 Free PMC article.
Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters.
Rouers A, Wong N, Goh YS, Torres-Ruesta A, Tay MZ, Chang ZW, Fong SW, Neo V, Kam IKJ, Yeo NK, Huang Y, Loh CY, Hor PX, Wong JXE, Tan YJ; COVID-19 Study Group; Macary PA, Qian X, Bei W, Ngoh EZX, Salleh SNM, Wang CI, Poh XY, Rao S, Chia PY, Ong SWX, Lee TH, Lin RJH, Lim C, Teo J, Ren EC, Lye DC, Young BE, Ng LFP, Renia L. Rouers A, et al. J Med Virol. 2023 Jan;95(1):e28258. doi: 10.1002/jmv.28258. Epub 2022 Nov 16. J Med Virol. 2023. PMID: 36305052 Free PMC article.
Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice.
Salzer R, Clark JJ, Vaysburd M, Chang VT, Albecka A, Kiss L, Sharma P, Gonzalez Llamazares A, Kipar A, Hiscox JA, Owen A, Aricescu AR, Stewart JP, James LC, Löwe J. Salzer R, et al. FEBS Lett. 2021 Sep;595(18):2323-2340. doi: 10.1002/1873-3468.14171. Epub 2021 Aug 22. FEBS Lett. 2021. PMID: 34331769 Free PMC article.