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Nanoparticle-Mediated Delivery of Anti-PU.1 siRNA via Localized Intracisternal Administration Reduces Neuroinflammation.
Adv Mater. 2024 Feb;36(8):e2309225. doi: 10.1002/adma.202309225. Epub 2023 Dec 8.
Adv Mater. 2024.
PMID: 38018280
A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation.
Ralvenius WT, Mungenast AE, Woolf H, Huston MM, Gillingham TZ, Godin SK, Penney J, Cam HP, Gao F, Fernandez CG, Czako B, Lightfoot Y, Ray WJ, Beckmann A, Goate AM, Marcora E, Romero-Molina C, Ayata P, Schaefer A, Gjoneska E, Tsai LH.
Ralvenius WT, et al.
J Exp Med. 2023 Nov 6;220(11):e20222105. doi: 10.1084/jem.20222105. Epub 2023 Aug 29.
J Exp Med. 2023.
PMID: 37642942
Free PMC article.
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