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Associations of plasma neurofilament light chain and progranulin with frailty in older adults.
J Am Geriatr Soc. 2022 Apr;70(4):1236-1243. doi: 10.1111/jgs.17604. Epub 2021 Dec 15.
J Am Geriatr Soc. 2022.
PMID: 34908159
Clinical Trial.
METHODS: We included 507 older adults (mean [standard deviation] age, 76.7 [4.5] years) with plasma NfL and PGRN measurements from the Multidomain Alzheimer Preventive Trial (MAPT). The timepoint of biomarker measurements, either 12 or 24 months after study enrollme …
METHODS: We included 507 older adults (mean [standard deviation] age, 76.7 [4.5] years) with plasma NfL and PGRN measurements from the Multi …
Association between physical activity, growth differentiation factor 15 and bodyweight in older adults: A longitudinal mediation analysis.
Raffin J, Rolland Y, Parini A, Lucas A, Guyonnet S, Vellas B, de Souto Barreto P; MAPT/DSA Group.
Raffin J, et al.
J Cachexia Sarcopenia Muscle. 2023 Jan 20;14(2):771-80. doi: 10.1002/jcsm.13152. Online ahead of print.
J Cachexia Sarcopenia Muscle. 2023.
PMID: 36999490
Free PMC article.
BACKGROUND: Late-life aging is often associated with appetite reduction and weight loss. Physical activity (PA) may prevent these processes, but the molecular mechanisms involved remain elusive. ...METHODS: One thousand eighty-three healthy adults (63.8% women) aged 70 yea …
BACKGROUND: Late-life aging is often associated with appetite reduction and weight loss. Physical activity (PA) may prevent these pro …
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