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Association between physical activity, growth differentiation factor 15 and bodyweight in older adults: A longitudinal mediation analysis.
J Cachexia Sarcopenia Muscle. 2023 Jan 20;14(2):771-80. doi: 10.1002/jcsm.13152. Online ahead of print.
J Cachexia Sarcopenia Muscle. 2023.
PMID: 36999490
Free PMC article.
The present study investigated the putative mediating aspect of growth differentiation factor 15 (GDF-15), a stress signalling protein involved in aging, exercise and appetite control, on the association between PA and late-life-associated weight loss. METHODS: One …
The present study investigated the putative mediating aspect of growth differentiation factor 15 (GDF-15), a stress signalling protein invol …
Associations of plasma neurofilament light chain and progranulin with frailty in older adults.
Lu WH, Giudici KV, Guyonnet S, Aggarwal G, Nguyen AD, Morley JE, Vellas B, de Souto Barreto P; MAPT/DSA Group.
Lu WH, et al.
J Am Geriatr Soc. 2022 Apr;70(4):1236-1243. doi: 10.1111/jgs.17604. Epub 2021 Dec 15.
J Am Geriatr Soc. 2022.
PMID: 34908159
Clinical Trial.
BACKGROUND: In previous studies, plasma neurofilament light chain (NfL) and progranulin (PGRN) levels are associated with cognitive and physical impairment in older individuals. ...Neither NfL nor PGRN levels showed prospective associations with incident frailty ove …
BACKGROUND: In previous studies, plasma neurofilament light chain (NfL) and progranulin (PGRN) levels are associated with cognitive a …
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