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Page 1
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation.
Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, Fischer ES, Bradley A, Vassiliou GS, Slack FJ, Tzelepis K, Gregory RI. Orellana EA, et al. Mol Cell. 2021 Aug 19;81(16):3323-3338.e14. doi: 10.1016/j.molcel.2021.06.031. Epub 2021 Aug 4. Mol Cell. 2021. PMID: 34352207 Free PMC article.
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Hsu JI, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, Zhang J, Heffernan TP, Gera S, Kovacs JJ, Marszalek JR, Bristow C, Yan Y, Garcia-Manero G, Kantarjian H, Vassiliou G, Futreal PA, Donehower LA, Takahashi K, Goodell MA. Hsu JI, et al. Cell Stem Cell. 2018 Nov 1;23(5):700-713.e6. doi: 10.1016/j.stem.2018.10.004. Cell Stem Cell. 2018. PMID: 30388424 Free PMC article.
Mouse Models of Myeloid Malignancies.
Basheer F, Vassiliou G. Basheer F, et al. Cold Spring Harb Perspect Med. 2021 Jan 4;11(1):a035535. doi: 10.1101/cshperspect.a035535. Cold Spring Harb Perspect Med. 2021. PMID: 32071146 Free PMC article. Review.
SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD-mutant AML.
Pacharne S, Dovey OM, Cooper JL, Gu M, Friedrich MJ, Rajan SS, Barenboim M, Collord G, Vijayabaskar MS, Ponstingl H, De Braekeleer E, Bautista R, Mazan M, Rad R, Tzelepis K, Wright P, Gozdecka M, Vassiliou GS. Pacharne S, et al. Blood Adv. 2021 May 11;5(9):2412-2425. doi: 10.1182/bloodadvances.2020003443. Blood Adv. 2021. PMID: 33956058 Free PMC article.
Concordance for clonal hematopoiesis is limited in elderly twins.
Fabre MA, McKerrell T, Zwiebel M, Vijayabaskar MS, Park N, Wells PM, Rad R, Deloukas P, Small K, Steves CJ, Vassiliou GS. Fabre MA, et al. Blood. 2020 Jan 23;135(4):269-273. doi: 10.1182/blood.2019001807. Blood. 2020. PMID: 31697828 Free PMC article.