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A multi-centre, double-blind, placebo-controlled, randomised trial of combination methotrexate and gefitinib versus methotrexate alone to treat tubal ectopic pregnancies (GEM3): trial protocol.
May J, Duncan C, Mol B, Bhattacharya S, Daniels J, Middleton L, Hewitt C, Coomarasamy A, Jurkovic D, Bourne T, Bottomley C, Peace-Gadsby A, Doust A, Tong S, Horne AW. May J, et al. Trials. 2018 Nov 20;19(1):643. doi: 10.1186/s13063-018-3008-6. Trials. 2018. PMID: 30458863 Free PMC article.
Gefitinib and Methotrexate to Treat Ectopic Pregnancies with a Pre-Treatment Serum hCG 1000-10,000 IU/L: Phase II Open Label, Single Arm Multi-Centre Trial.
Skubisz MM, Tong S, Doust A, Mollison J, Johns TG, Neil P, Robinson M, Bhattacharya S, Wallace E, Krzys N, Colin Duncan W, Horne AW. Skubisz MM, et al. EBioMedicine. 2018 Jul;33:276-281. doi: 10.1016/j.ebiom.2018.06.017. Epub 2018 Jun 22. EBioMedicine. 2018. PMID: 29941341 Free PMC article. Clinical Trial.