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Atlas of Circadian Metabolism Reveals System-wide Coordination and Communication between Clocks.
Dyar KA, Lutter D, Artati A, Ceglia NJ, Liu Y, Armenta D, Jastroch M, Schneider S, de Mateo S, Cervantes M, Abbondante S, Tognini P, Orozco-Solis R, Kinouchi K, Wang C, Swerdloff R, Nadeef S, Masri S, Magistretti P, Orlando V, Borrelli E, Uhlenhaut NH, Baldi P, Adamski J, Tschöp MH, Eckel-Mahan K, Sassone-Corsi P. Dyar KA, et al. Cell. 2018 Sep 6;174(6):1571-1585.e11. doi: 10.1016/j.cell.2018.08.042. Cell. 2018. PMID: 30193114 Free PMC article.
Tryptophan metabolism is a physiological integrator regulating circadian rhythms.
Petrus P, Cervantes M, Samad M, Sato T, Chao A, Sato S, Koronowski KB, Park G, Alam Y, Mejhert N, Seldin MM, Monroy Kuhn JM, Dyar KA, Lutter D, Baldi P, Kaiser P, Jang C, Sassone-Corsi P. Petrus P, et al. Mol Metab. 2022 Oct;64:101556. doi: 10.1016/j.molmet.2022.101556. Epub 2022 Jul 29. Mol Metab. 2022. PMID: 35914650 Free PMC article.
The central clock suffices to drive the majority of circulatory metabolic rhythms.
Petrus P, Smith JG, Koronowski KB, Chen S, Sato T, Greco CM, Mortimer T, Welz PS, Zinna VM, Shimaji K, Cervantes M, Punzo D, Baldi P, Muñoz-Cánoves P, Sassone-Corsi P, Benitah SA. Petrus P, et al. Sci Adv. 2022 Jul;8(26):eabo2896. doi: 10.1126/sciadv.abo2896. Epub 2022 Jun 29. Sci Adv. 2022. PMID: 35767612 Free PMC article.