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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1973 1
1976 1
1978 1
1980 2
1981 1
1985 2
1986 2
1987 2
1988 1
1989 1
1990 1
1992 1
1993 2
1994 7
1995 4
1996 4
1997 16
1998 8
1999 10
2000 7
2001 17
2002 13
2003 13
2004 11
2005 18
2006 15
2007 22
2008 10
2009 15
2010 15
2011 12
2012 11
2013 13
2014 17
2015 27
2016 20
2017 17
2018 17
2019 35
2020 31
2021 43
2022 48
2023 56
2024 30

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559 results

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Page 1
Evidence-based clinical practice guidelines for Liver Cirrhosis 2020.
Yoshiji H, Nagoshi S, Akahane T, Asaoka Y, Ueno Y, Ogawa K, Kawaguchi T, Kurosaki M, Sakaida I, Shimizu M, Taniai M, Terai S, Nishikawa H, Hiasa Y, Hidaka H, Miwa H, Chayama K, Enomoto N, Shimosegawa T, Takehara T, Koike K. Yoshiji H, et al. J Gastroenterol. 2021 Jul;56(7):593-619. doi: 10.1007/s00535-021-01788-x. Epub 2021 Jul 7. J Gastroenterol. 2021. PMID: 34231046 Free PMC article. Review.
It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, …
It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, …
Evidence-based clinical practice guidelines for cholelithiasis 2021.
Fujita N, Yasuda I, Endo I, Isayama H, Iwashita T, Ueki T, Uemura K, Umezawa A, Katanuma A, Katayose Y, Suzuki Y, Shoda J, Tsuyuguchi T, Wakai T, Inui K, Unno M, Takeyama Y, Itoi T, Koike K, Mochida S. Fujita N, et al. J Gastroenterol. 2023 Sep;58(9):801-833. doi: 10.1007/s00535-023-02014-6. Epub 2023 Jul 15. J Gastroenterol. 2023. PMID: 37452855 Free PMC article. Review.
The clinical questions (CQ) in the previous version were reviewed and rearranged into three newly divided categories: background questions (BQ) dealing with basic background knowledge, CQ, and future research questions (FRQ), which refer to issues that require further accu …
The clinical questions (CQ) in the previous version were reviewed and rearranged into three newly divided categories: background questions ( …
Molecular Regulation of Circadian Chromatin.
Zhu Q, Belden WJ. Zhu Q, et al. J Mol Biol. 2020 May 29;432(12):3466-3482. doi: 10.1016/j.jmb.2020.01.009. Epub 2020 Jan 16. J Mol Biol. 2020. PMID: 31954735 Review.
In Neurospora, the rhythm in facultative heterochromatin is mediated by the frequency (frq) natural antisense transcript (NAT) qrf. While in mammals, histone deacetylases (HDACs), histone H3 lysine 9 methyltransferase (KMT1/SUV39), and components of nucleosome remodeling a …
In Neurospora, the rhythm in facultative heterochromatin is mediated by the frequency (frq) natural antisense transcript (NAT) qrf. W …
The neurospora circadian system.
Dunlap JC, Loros JJ. Dunlap JC, et al. J Biol Rhythms. 2004 Oct;19(5):414-24. doi: 10.1177/0748730404269116. J Biol Rhythms. 2004. PMID: 15534321 Review.
Phosphorylation of FRQ by several kinases leads to its ubiquitination and turnover, releasing the WC-1/WC-2 dimer to reactivate frq expression and restart the circadian cycle. ...Several FRQ- and WC-independent, noncircadian FRQ-less oscillators (FLOs) …
Phosphorylation of FRQ by several kinases leads to its ubiquitination and turnover, releasing the WC-1/WC-2 dimer to reactivate fr …
FRQ-CK1 Interaction Underlies Temperature Compensation of the Neurospora Circadian Clock.
Hu Y, Liu X, Lu Q, Yang Y, He Q, Liu Y, Liu X. Hu Y, et al. mBio. 2021 Jun 29;12(3):e0142521. doi: 10.1128/mBio.01425-21. Epub 2021 Jun 29. mBio. 2021. PMID: 34182774 Free PMC article.
Formation of a stable complex between clock proteins and casein kinase 1 (CK1) is a conserved feature in eukaryotic circadian mechanisms. Here, we show that the FRQ-CK1 interaction and CK1-mediated FRQ phosphorylation, not FRQ stability, are main mechanisms r …
Formation of a stable complex between clock proteins and casein kinase 1 (CK1) is a conserved feature in eukaryotic circadian mechanisms. He …
Making Time: Conservation of Biological Clocks from Fungi to Animals.
Dunlap JC, Loros JJ. Dunlap JC, et al. Microbiol Spectr. 2017 May;5(3):10.1128/microbiolspec.FUNK-0039-2016. doi: 10.1128/microbiolspec.FUNK-0039-2016. Microbiol Spectr. 2017. PMID: 28527179 Free PMC article. Review.
In Neurospora, the best studied fungal model, it is driven by two transcription factors, WC-1 and WC-2, that form the White Collar Complex (WCC). WCC elicits expression of the frq gene. FRQ complexes with other proteins, physically interacts with the WCC, and reduce …
In Neurospora, the best studied fungal model, it is driven by two transcription factors, WC-1 and WC-2, that form the White Collar Complex ( …
Differential regulation of phosphorylation, structure, and stability of circadian clock protein FRQ isoforms.
Chen X, Liu X, Gan X, Li S, Ma H, Zhang L, Wang P, Li Y, Huang T, Yang X, Fang L, Liang Y, Wu J, Chen T, Zhou Z, Liu X, Guo J. Chen X, et al. J Biol Chem. 2023 Apr;299(4):104597. doi: 10.1016/j.jbc.2023.104597. Epub 2023 Mar 9. J Biol Chem. 2023. PMID: 36898580 Free PMC article.
Neurospora crassa is an important model organism for circadian clock research. The Neurospora core circadian component FRQ protein has two isoforms, large FRQ (l-FRQ) and small FRQ (s-FRQ), of which l-FRQ bears an additional N-terminal 99 …
Neurospora crassa is an important model organism for circadian clock research. The Neurospora core circadian component FRQ protein ha …
Evidence-based clinical practice guidelines for liver cirrhosis 2020.
Yoshiji H, Nagoshi S, Akahane T, Asaoka Y, Ueno Y, Ogawa K, Kawaguchi T, Kurosaki M, Sakaida I, Shimizu M, Taniai M, Terai S, Nishikawa H, Hiasa Y, Hidaka H, Miwa H, Chayama K, Enomoto N, Shimosegawa T, Takehara T, Koike K. Yoshiji H, et al. Hepatol Res. 2021 Jul;51(7):725-749. doi: 10.1111/hepr.13678. Epub 2021 Jul 6. Hepatol Res. 2021. PMID: 34228859
It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, ascites, hepatorenal syndrome and acute kidney injury, hepatic encephalopathy, portal thrombus, sarcopenia, muscle cramp, thrombocytopenia, …
It also covers the latest evidence regarding the diagnosis and treatment of liver cirrhosis complications, namely gastrointestinal bleeding, …
559 results