HL29307/HL/NHLBI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
1984	1
1987	2
1988	1
1989	2
1991	1
1992	4
1993	3
1994	6
1995	3
1996	1
1998	2
2024	0

1

Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.

Jackson DS, Fraser SA, Ni LM, Kam CM, Winkler U, Johnson DA, Froelich CJ, Hudig D, Powers JC. Jackson DS, et al. J Med Chem. 1998 Jun 18;41(13):2289-301. doi: 10.1021/jm970543s. J Med Chem. 1998. PMID: 9632362

2

Dipeptide phosphonates as inhibitors of dipeptidyl peptidase IV.

Boduszek B, Oleksyszyn J, Kam CM, Selzler J, Smith RE, Powers JC. Boduszek B, et al. J Med Chem. 1994 Nov 11;37(23):3969-76. doi: 10.1021/jm00049a016. J Med Chem. 1994. PMID: 7966157

3

Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors.

Bode W, Meyer E Jr, Powers JC. Bode W, et al. Biochemistry. 1989 Mar 7;28(5):1951-63. doi: 10.1021/bi00431a001. Biochemistry. 1989. PMID: 2655701 Review. No abstract available.

4

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.

Odake S, Kam CM, Narasimhan L, Poe M, Blake JT, Krahenbuhl O, Tschopp J, Powers JC. Odake S, et al. Biochemistry. 1991 Feb 26;30(8):2217-27. doi: 10.1021/bi00222a027. Biochemistry. 1991. PMID: 1998680

5

Catalysis by human leukocyte elastase: proton inventory as a mechanistic probe.

Stein RL, Strimpler AM, Hori H, Powers JC. Stein RL, et al. Biochemistry. 1987 Mar 10;26(5):1305-14. doi: 10.1021/bi00379a016. Biochemistry. 1987. PMID: 3032250

6

Substrate and inhibitor studies on proteinase 3.

Kam CM, Kerrigan JE, Dolman KM, Goldschmeding R, Von dem Borne AE, Powers JC. Kam CM, et al. FEBS Lett. 1992 Feb 3;297(1-2):119-23. doi: 10.1016/0014-5793(92)80340-m. FEBS Lett. 1992. PMID: 1551417 Free article.

7

Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases.

Oleksyszyn J, Boduszek B, Kam CM, Powers JC. Oleksyszyn J, et al. J Med Chem. 1994 Jan 21;37(2):226-31. doi: 10.1021/jm00028a004. J Med Chem. 1994. PMID: 8295209

8

Isocoumarin inhibitors of serine peptidases.

Powers JC, Kam CM. Powers JC, et al. Methods Enzymol. 1994;244:442-57. doi: 10.1016/0076-6879(94)44033-6. Methods Enzymol. 1994. PMID: 7845225 No abstract available.

9

Localization, implications for function, and gene expression of chymotrypsin-like proteinases of cytotoxic RNK-16 lymphocytes.

Zunino SJ, Allison NJ, Kam CM, Powers JC, Hudig D. Zunino SJ, et al. Biochim Biophys Acta. 1988 Dec 15;967(3):331-40. doi: 10.1016/0304-4165(88)90095-5. Biochim Biophys Acta. 1988. PMID: 3264187

10

Inhibition of trypsin and thrombin by amino(4-amidinophenyl)methanephosphonate diphenyl ester derivatives: X-ray structures and molecular models.

Bertrand JA, Oleksyszyn J, Kam CM, Boduszek B, Presnell S, Plaskon RR, Suddath FL, Powers JC, Williams LD. Bertrand JA, et al. Biochemistry. 1996 Mar 12;35(10):3147-55. doi: 10.1021/bi9520996. Biochemistry. 1996. PMID: 8605148

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