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1997 | 1 |
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Activation of factor VIII by thrombin increases its affinity for binding to synthetic phospholipid membranes and activated platelets.
J Biol Chem. 1998 Oct 23;273(43):27918-26. doi: 10.1074/jbc.273.43.27918.
J Biol Chem. 1998.
PMID: 9774404
Free article.
Detection of all anti-factor VIII antibodies in haemophilia A patients by the Bethesda assay and a more sensitive immunoprecipitation assay.
Klinge J, Auerswald G, Budde U, Klose H, Kreuz W, Lenk H, Scandella D; Paediatric Inhibitor Study Group of the German Society on Thrombosis and Haemostasis.
Klinge J, et al.
Haemophilia. 2001 Jan;7(1):26-32. doi: 10.1046/j.1365-2516.2001.00456.x.
Haemophilia. 2001.
PMID: 11136377
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The acidic region of the factor VIII light chain and the C2 domain together form the high affinity binding site for von willebrand factor.
Saenko EL, Scandella D.
Saenko EL, et al.
J Biol Chem. 1997 Jul 18;272(29):18007-14. doi: 10.1074/jbc.272.29.18007.
J Biol Chem. 1997.
PMID: 9218428
Free article.
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Dominant C2 domain epitope specificity of inhibitor antibodies elicited by a heat pasteurized product, factor VIII CPS-P, in previously treated hemophilia A patients without inhibitors.
Sawamoto Y, Prescott R, Zhong D, Saenko EL, Mauser-Bunschoten E, Peerlinck K, van den Berg M, Scandella D.
Sawamoto Y, et al.
Thromb Haemost. 1998 Jan;79(1):62-8.
Thromb Haemost. 1998.
PMID: 9459325
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Inhibitors in German hemophilia A patients treated with a double virus inactivated factor VIII concentrate bind to the C2 domain of FVIII light chain.
Laub R, Di Giambattista M, Fondu P, Brackmann HH, Lenk H, Saenko EL, Felch M, Scandella D.
Laub R, et al.
Thromb Haemost. 1999 Jan;81(1):39-44.
Thromb Haemost. 1999.
PMID: 9974372
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