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Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.
Fares I, Chagraoui J, Gareau Y, Gingras S, Ruel R, Mayotte N, Csaszar E, Knapp DJ, Miller P, Ngom M, Imren S, Roy DC, Watts KL, Kiem HP, Herrington R, Iscove NN, Humphries RK, Eaves CJ, Cohen S, Marinier A, Zandstra PW, Sauvageau G. Fares I, et al. Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337. Science. 2014. PMID: 25237102 Free PMC article.
Myeloablative irradiation in non-human primates.
Watts KL, Beard BC, Wood BL, Kiem HP. Watts KL, et al. J Med Primatol. 2009 Dec;38(6):425-32. doi: 10.1111/j.1600-0684.2009.00368.x. Epub 2009 Jul 22. J Med Primatol. 2009. PMID: 19638102 Free PMC article.