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Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials.
Acad Emerg Med. 2008 May;15(5):399-413. doi: 10.1111/j.1553-2712.2008.00109.x.
Acad Emerg Med. 2008.
PMID: 18439194
Free PMC article.
Review.
Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis.
Trzeciak S, McCoy JV, Phillip Dellinger R, Arnold RC, Rizzuto M, Abate NL, Shapiro NI, Parrillo JE, Hollenberg SM; Microcirculatory Alterations in Resuscitation and Shock (MARS) investigators.
Trzeciak S, et al.
Intensive Care Med. 2008 Dec;34(12):2210-7. doi: 10.1007/s00134-008-1193-6. Epub 2008 Jul 2.
Intensive Care Med. 2008.
PMID: 18594793
Free PMC article.
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Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality.
Kilgannon JH, Roberts BW, Reihl LR, Chansky ME, Jones AE, Dellinger RP, Parrillo JE, Trzeciak S.
Kilgannon JH, et al.
Resuscitation. 2008 Dec;79(3):410-6. doi: 10.1016/j.resuscitation.2008.07.019. Epub 2008 Nov 5.
Resuscitation. 2008.
PMID: 18990478
Free PMC article.
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