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A multi-tissue atlas of regulatory variants in cattle.
Liu S, Gao Y, Canela-Xandri O, Wang S, Yu Y, Cai W, Li B, Xiang R, Chamberlain AJ, Pairo-Castineira E, D'Mellow K, Rawlik K, Xia C, Yao Y, Navarro P, Rocha D, Li X, Yan Z, Li C, Rosen BD, Van Tassell CP, Vanraden PM, Zhang S, Ma L, Cole JB, Liu GE, Tenesa A, Fang L. Liu S, et al. Nat Genet. 2022 Sep;54(9):1438-1447. doi: 10.1038/s41588-022-01153-5. Epub 2022 Aug 11. Nat Genet. 2022. PMID: 35953587 Free PMC article.
Sex differences in genetic architecture in the UK Biobank.
Bernabeu E, Canela-Xandri O, Rawlik K, Talenti A, Prendergast J, Tenesa A. Bernabeu E, et al. Nat Genet. 2021 Sep;53(9):1283-1289. doi: 10.1038/s41588-021-00912-0. Epub 2021 Sep 7. Nat Genet. 2021. PMID: 34493869
An atlas of genetic associations in UK Biobank.
Canela-Xandri O, Rawlik K, Tenesa A. Canela-Xandri O, et al. Nat Genet. 2018 Nov;50(11):1593-1599. doi: 10.1038/s41588-018-0248-z. Epub 2018 Oct 22. Nat Genet. 2018. PMID: 30349118 Free PMC article.
Comprehensive analyses of 723 transcriptomes enhance genetic and biological interpretations for complex traits in cattle.
Fang L, Cai W, Liu S, Canela-Xandri O, Gao Y, Jiang J, Rawlik K, Li B, Schroeder SG, Rosen BD, Li CJ, Sonstegard TS, Alexander LJ, Van Tassell CP, VanRaden PM, Cole JB, Yu Y, Zhang S, Tenesa A, Ma L, Liu GE. Fang L, et al. Genome Res. 2020 May;30(5):790-801. doi: 10.1101/gr.250704.119. Epub 2020 May 18. Genome Res. 2020. PMID: 32424068 Free PMC article.
Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.
Bretherick AD, Canela-Xandri O, Joshi PK, Clark DW, Rawlik K, Boutin TS, Zeng Y, Amador C, Navarro P, Rudan I, Wright AF, Campbell H, Vitart V, Hayward C, Wilson JF, Tenesa A, Ponting CP, Baillie JK, Haley C. Bretherick AD, et al. PLoS Genet. 2020 Jul 6;16(7):e1008785. doi: 10.1371/journal.pgen.1008785. eCollection 2020 Jul. PLoS Genet. 2020. PMID: 32628676 Free PMC article.
Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.
Zeng Y, Amador C, Xia C, Marioni R, Sproul D, Walker RM, Morris SW, Bretherick A, Canela-Xandri O, Boutin TS, Clark DW, Campbell A, Rawlik K, Hayward C, Nagy R, Tenesa A, Porteous DJ, Wilson JF, Deary IJ, Evans KL, McIntosh AM, Navarro P, Haley CS. Zeng Y, et al. Nat Commun. 2019 Mar 27;10(1):1383. doi: 10.1038/s41467-019-09301-y. Nat Commun. 2019. PMID: 30918249 Free PMC article.