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2020 1
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Page 1
DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood.
Issarapu P, Arumalla M, Elliott HR, Nongmaithem SS, Sankareswaran A, Betts M, Sajjadi S, Kessler NJ, Bayyana S, Mansuri SR, Derakhshan M, Krishnaveni GV, Shrestha S, Kumaran K, Di Gravio C, Sahariah SA, Sanderson E, Relton CL, Ward KA, Moore SE, Prentice AM, Lillycrop KA, Fall CHD, Silver MJ, Chandak GR; EMPHASIS study group. Issarapu P, et al. Nat Commun. 2023 Aug 25;14(1):5200. doi: 10.1038/s41467-023-40607-0. Nat Commun. 2023. PMID: 37626025 Free PMC article.
Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment.
Lechner L, Opitz R, Silver MJ, Krabusch PM, Prentice AM, Field MS, Stachelscheid H, Leitão E, Schröder C, Fernandez Vallone V, Horsthemke B, Jöckel KH, Schmidt B, Nöthen MM, Hoffmann P, Herms S, Kleyn PW, Megges M, Blume-Peytavi U, Weiss K, Mai K, Blankenstein O, Obermayer B, Wiegand S, Kühnen P. Lechner L, et al. Sci Transl Med. 2023 Jul 19;15(705):eadg1659. doi: 10.1126/scitranslmed.adg1659. Epub 2023 Jul 19. Sci Transl Med. 2023. PMID: 37467315
A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation.
Li S, Spitz N, Ghantous A, Abrishamcar S, Reimann B, Marques I, Silver MJ, Aguilar-Lacasaña S, Kitaba N, Rezwan FI, Röder S, Sirignano L, Tuhkanen J, Mancano G, Sharp GC, Metayer C, Morimoto L, Stein DJ, Zar HJ, Alfano R, Nawrot T, Wang C, Kajantie E, Keikkala E, Mustaniemi S, Ronkainen J, Sebert S, Silva W, Vääräsmäki M, Jaddoe VWV, Bernstein RM, Prentice AM, Cosin-Tomas M, Dwyer T, Håberg SE, Herceg Z, Magnus MC, Munthe-Kaas MC, Page CM, Völker M, Gilles M, Send T, Witt S, Zillich L, Gagliardi L, Richiardi L, Czamara D, Räikkönen K, Chatzi L, Vafeiadi M, Arshad SH, Ewart S, Plusquin M, Felix JF, Moore SE, Vrijheid M, Holloway JW, Karmaus W, Herberth G, Zenclussen A, Streit F, Lahti J, Hüls A, Hoang TT, London SJ, Wiemels JL. Li S, et al. Commun Biol. 2024 Jan 9;7(1):66. doi: 10.1038/s42003-023-05698-x. Commun Biol. 2024. PMID: 38195839 Free PMC article.
Environmentally sensitive hotspots in the methylome of the early human embryo.
Silver MJ, Saffari A, Kessler NJ, Chandak GR, Fall CHD, Issarapu P, Dedaniya A, Betts M, Moore SE, Routledge MN, Herceg Z, Cuenin C, Derakhshan M, James PT, Monk D, Prentice AM. Silver MJ, et al. Elife. 2022 Feb 21;11:e72031. doi: 10.7554/eLife.72031. Elife. 2022. PMID: 35188105 Free PMC article.
Effect of maternal preconceptional and pregnancy micronutrient interventions on children's DNA methylation: Findings from the EMPHASIS study.
Saffari A, Shrestha S, Issarapu P, Sajjadi S, Betts M, Sahariah SA, Tomar AS, James P, Dedaniya A, Yadav DK, Kumaran K, Prentice AM, Lillycrop KA, Fall CHD, Chandak GR, Silver MJ; EMPHASIS Study Group. Saffari A, et al. Am J Clin Nutr. 2020 Oct 1;112(4):1099-1113. doi: 10.1093/ajcn/nqaa193. Am J Clin Nutr. 2020. PMID: 32889533 Free PMC article.
Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA.
Quilter CR, Harvey KM, Bauer J, Skinner BM, Gomez M, Shrivastava M, Doel AM, Drammeh S, Dunger DB, Moore SE, Ong KK, Prentice AM, Bernstein RM, Sargent CA, Affara NA. Quilter CR, et al. FASEB Bioadv. 2021 Feb 5;3(4):205-230. doi: 10.1096/fba.2020-00101. eCollection 2021 Apr. FASEB Bioadv. 2021. PMID: 33842847 Free PMC article.
DNA methylation signatures associated with cardiometabolic risk factors in children from India and The Gambia: results from the EMPHASIS study.
Antoun E, Issarapu P, di Gravio C, Shrestha S, Betts M, Saffari A, Sahariah SA, Sankareswaran A, Arumalla M, Prentice AM, Fall CHD, Silver MJ, Chandak GR, Lillycrop KA; EMPHASIS study group. Antoun E, et al. Clin Epigenetics. 2022 Jan 9;14(1):6. doi: 10.1186/s13148-021-01213-3. Clin Epigenetics. 2022. PMID: 35000590 Free PMC article.