N01CM42216/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2008	1
2009	5
2010	19
2011	23
2012	18
2013	15
2014	16
2015	14
2016	11
2017	7
2018	1
2019	2
2022	1
2024	0

1

Preclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and Validation.

Geier B, Kurmashev D, Kurmasheva RT, Houghton PJ. Geier B, et al. Front Oncol. 2015 Aug 26;5:193. doi: 10.3389/fonc.2015.00193. eCollection 2015. Front Oncol. 2015. PMID: 26380223 Free PMC article. Review.

2

P53 suppresses ribonucleotide reductase via inhibiting mTORC1.

He Z, Hu X, Liu W, Dorrance A, Garzon R, Houghton PJ, Shen C. He Z, et al. Oncotarget. 2017 Jun 20;8(25):41422-41431. doi: 10.18632/oncotarget.17440. Oncotarget. 2017. PMID: 28507282 Free PMC article.

3

Synergism of FAK and tyrosine kinase inhibition in Ph⁺ B-ALL.

Churchman ML, Evans K, Richmond J, Robbins A, Jones L, Shapiro IM, Pachter JA, Weaver DT, Houghton PJ, Smith MA, Lock RB, Mullighan CG. Churchman ML, et al. JCI Insight. 2016;1(4):e86082. doi: 10.1172/jci.insight.86082. Epub 2016 Apr 7. JCI Insight. 2016. PMID: 27123491 Free PMC article.

4

Approaches to identifying drug resistance mechanisms to clinically relevant treatments in childhood rhabdomyosarcoma.

Ghilu S, Morton CL, Vaseva AV, Zheng S, Kurmasheva RT, Houghton PJ. Ghilu S, et al. Cancer Drug Resist. 2022;5(1):80-89. doi: 10.20517/cdr.2021.112. Epub 2022 Jan 4. Cancer Drug Resist. 2022. PMID: 35450020 Free PMC article.

5

Drug discovery in paediatric oncology: roadblocks to progress.

Adamson PC, Houghton PJ, Perilongo G, Pritchard-Jones K. Adamson PC, et al. Nat Rev Clin Oncol. 2014 Dec;11(12):732-9. doi: 10.1038/nrclinonc.2014.149. Epub 2014 Sep 16. Nat Rev Clin Oncol. 2014. PMID: 25223555 Free PMC article. Review.

6

Radiation therapy may increase metastatic potential in alveolar rhabdomyosarcoma.

Woods GM, Bondra K, Chronowski C, Leasure J, Singh M, Hensley L, Cripe TP, Chakravarti A, Houghton P. Woods GM, et al. Pediatr Blood Cancer. 2015 Sep;62(9):1550-1554. doi: 10.1002/pbc.25516. Epub 2015 Mar 19. Pediatr Blood Cancer. 2015. PMID: 25790258 Free PMC article.

7

Regulation of CHK1 by mTOR contributes to the evasion of DNA damage barrier of cancer cells.

Zhou X, Liu W, Hu X, Dorrance A, Garzon R, Houghton PJ, Shen C. Zhou X, et al. Sci Rep. 2017 May 8;7(1):1535. doi: 10.1038/s41598-017-01729-w. Sci Rep. 2017. PMID: 28484242 Free PMC article.

8

The mTOR pathway negatively controls ATM by up-regulating miRNAs.

Shen C, Houghton PJ. Shen C, et al. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11869-74. doi: 10.1073/pnas.1220898110. Epub 2013 Jul 1. Proc Natl Acad Sci U S A. 2013. PMID: 23818585 Free PMC article.

9

Acute Sensitivity of Ph-like Acute Lymphoblastic Leukemia to the SMAC-Mimetic Birinapant.

Richmond J, Robbins A, Evans K, Beck D, Kurmasheva RT, Billups CA, Carol H, Heatley S, Sutton R, Marshall GM, White D, Pimanda J, Houghton PJ, Smith MA, Lock RB. Richmond J, et al. Cancer Res. 2016 Aug 1;76(15):4579-91. doi: 10.1158/0008-5472.CAN-16-0523. Epub 2016 Jun 14. Cancer Res. 2016. PMID: 27302164 Free PMC article.

10

Initial Testing (Stage 1) of MK-8242-A Novel MDM2 Inhibitor-by the Pediatric Preclinical Testing Program.

Kang MH, Reynolds CP, Kolb EA, Gorlick R, Carol H, Lock R, Keir ST, Maris JM, Wu J, Lyalin D, Kurmasheva RT, Houghton PJ, Smith MA. Kang MH, et al. Pediatr Blood Cancer. 2016 Oct;63(10):1744-52. doi: 10.1002/pbc.26064. Epub 2016 May 30. Pediatr Blood Cancer. 2016. PMID: 27238606 Free PMC article.

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