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2008 3
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Page 1
Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
Im SJ, Hashimoto M, Gerner MY, Lee J, Kissick HT, Burger MC, Shan Q, Hale JS, Lee J, Nasti TH, Sharpe AH, Freeman GJ, Germain RN, Nakaya HI, Xue HH, Ahmed R. Im SJ, et al. Nature. 2016 Sep 15;537(7620):417-421. doi: 10.1038/nature19330. Epub 2016 Aug 2. Nature. 2016. PMID: 27501248 Free PMC article.
Effector CD8 T cells dedifferentiate into long-lived memory cells.
Youngblood B, Hale JS, Kissick HT, Ahn E, Xu X, Wieland A, Araki K, West EE, Ghoneim HE, Fan Y, Dogra P, Davis CW, Konieczny BT, Antia R, Cheng X, Ahmed R. Youngblood B, et al. Nature. 2017 Dec 21;552(7685):404-409. doi: 10.1038/nature25144. Epub 2017 Dec 13. Nature. 2017. PMID: 29236683 Free PMC article.
Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, Owonikoko TK, Pillai RN, Ramalingam SS, Araki K, Ahmed R. Kamphorst AO, et al. Science. 2017 Mar 31;355(6332):1423-1427. doi: 10.1126/science.aaf0683. Epub 2017 Mar 9. Science. 2017. PMID: 28280249 Free PMC article.
Manipulating the PD-1 pathway to improve immunity.
Kamphorst AO, Ahmed R. Kamphorst AO, et al. Curr Opin Immunol. 2013 Jun;25(3):381-8. doi: 10.1016/j.coi.2013.03.003. Epub 2013 Apr 9. Curr Opin Immunol. 2013. PMID: 23582509 Free PMC article. Review.
The immunological synapse: the gateway to the HIV reservoir.
Kulpa DA, Brehm JH, Fromentin R, Cooper A, Cooper C, Ahlers J, Chomont N, Sékaly RP. Kulpa DA, et al. Immunol Rev. 2013 Jul;254(1):305-25. doi: 10.1111/imr.12080. Immunol Rev. 2013. PMID: 23772628 Free PMC article. Review.
68 results