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Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet.
Cheng CW, Biton M, Haber AL, Gunduz N, Eng G, Gaynor LT, Tripathi S, Calibasi-Kocal G, Rickelt S, Butty VL, Moreno-Serrano M, Iqbal AM, Bauer-Rowe KE, Imada S, Ulutas MS, Mylonas C, Whary MT, Levine SS, Basbinar Y, Hynes RO, Mino-Kenudson M, Deshpande V, Boyer LA, Fox JG, Terranova C, Rai K, Piwnica-Worms H, Mihaylova MM, Regev A, Yilmaz ÖH. Cheng CW, et al. Cell. 2019 Aug 22;178(5):1115-1131.e15. doi: 10.1016/j.cell.2019.07.048. Cell. 2019. PMID: 31442404 Free PMC article.
Cell size is a determinant of stem cell potential during aging.
Lengefeld J, Cheng CW, Maretich P, Blair M, Hagen H, McReynolds MR, Sullivan E, Majors K, Roberts C, Kang JH, Steiner JD, Miettinen TP, Manalis SR, Antebi A, Morrison SJ, Lees JA, Boyer LA, Yilmaz ÖH, Amon A. Lengefeld J, et al. Sci Adv. 2021 Nov 12;7(46):eabk0271. doi: 10.1126/sciadv.abk0271. Epub 2021 Nov 12. Sci Adv. 2021. PMID: 34767451 Free PMC article.
Post-fast refeeding enhances intestinal stem cell-mediated regeneration and tumourigenesis through mTORC1-dependent polyamine synthesis.
Imada S, Shin H, Khawaled S, Meckelmann SW, Whittaker CA, Corrêa RO, Pradhan D, Calibasi-Kocal G, Melo LMN, Allies G, Wittenhofer P, Schmitz OJ, Roper J, Vinolo MAR, Cheng CW, Tasdogan A, Yilmaz ÖH. Imada S, et al. Res Sq [Preprint]. 2023 Jan 10:rs.3.rs-2320717. doi: 10.21203/rs.3.rs-2320717/v1. Res Sq. 2023. PMID: 36711807 Free PMC article. Preprint.