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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.
Chour W, Choi J, Xie J, Chaffee ME, Schmitt TM, Finton K, DeLucia DC, Xu AM, Su Y, Chen DG, Zhang R, Yuan D, Hong S, Ng AHC, Butler JZ, Edmark RA, Jones LC, Murray KM, Peng S, Li G, Strong RK, Lee JK, Goldman JD, Greenberg PD, Heath JR. Chour W, et al. Commun Biol. 2023 May 16;6(1):528. doi: 10.1038/s42003-023-04899-8. Commun Biol. 2023. PMID: 37193826 Free PMC article.
Patient HLA Germline Variation and Transplant Survivorship.
Petersdorf EW, Stevenson P, Malkki M, Strong RK, Spellman SR, Haagenson MD, Horowitz MM, Gooley T, Wang T. Petersdorf EW, et al. J Clin Oncol. 2018 Aug 20;36(24):2524-2531. doi: 10.1200/JCO.2017.77.6534. Epub 2018 Jun 14. J Clin Oncol. 2018. PMID: 29902106 Free PMC article.
Effects of HLA single chain trimer design on peptide presentation and stability.
Finton KAK, Rupert PB, Friend DJ, Dinca A, Lovelace ES, Buerger M, Rusnac DV, Foote-McNabb U, Chour W, Heath JR, Campbell JS, Pierce RH, Strong RK. Finton KAK, et al. Front Immunol. 2023 May 3;14:1170462. doi: 10.3389/fimmu.2023.1170462. eCollection 2023. Front Immunol. 2023. PMID: 37207206 Free PMC article.
Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis.
Heath J, Chour W, Choi J, Xie J, Chaffee M, Schmitt T, Finton K, Delucia D, Xu A, Su Y, Chen D, Zhang R, Yuan D, Hong S, Ng A, Butler J, Edmark R, Jones L, Murray K, Peng S, Li G, Strong R, Lee J, Goldman J, Greenberg P. Heath J, et al. Res Sq [Preprint]. 2022 Nov 18:rs.3.rs-1090664. doi: 10.21203/rs.3.rs-1090664/v1. Res Sq. 2022. PMID: 36415462 Free PMC article. Updated. Preprint.
Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation.
Mao Z, Nesterenko PA, McLaughlin J, Deng W, Burton Sojo G, Cheng D, Noguchi M, Chour W, DeLucia DC, Finton KA, Qin Y, Obusan MB, Tran W, Wang L, Bangayan NJ, Ta L, Chen CC, Seet CS, Crooks GM, Phillips JW, Heath JR, Strong RK, Lee JK, Wohlschlegel JA, Witte ON. Mao Z, et al. Proc Natl Acad Sci U S A. 2022 Aug 2;119(31):e2203410119. doi: 10.1073/pnas.2203410119. Epub 2022 Jul 25. Proc Natl Acad Sci U S A. 2022. PMID: 35878026 Free PMC article.