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Engineered human cytokine/antibody fusion proteins expand regulatory T cells and confer autoimmune disease protection.
VanDyke D, Iglesias M, Tomala J, Young A, Smith J, Perry JA, Gebara E, Cross AR, Cheung LS, Dykema AG, Orcutt-Jahns BT, Henclová T, Golias J, Balolong J, Tomasovic LM, Funda D, Meyer AS, Pardoll DM, Hester J, Issa F, Hunter CA, Anderson MS, Bluestone JA, Raimondi G, Spangler JB. VanDyke D, et al. Cell Rep. 2022 Oct 18;41(3):111478. doi: 10.1016/j.celrep.2022.111478. Cell Rep. 2022. PMID: 36261022 Free PMC article.
The evolving role of T-bet in resistance to infection.
Pritchard GH, Kedl RM, Hunter CA. Pritchard GH, et al. Nat Rev Immunol. 2019 Jun;19(6):398-410. doi: 10.1038/s41577-019-0145-4. Nat Rev Immunol. 2019. PMID: 30846856 Free PMC article. Review.
PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection.
Perry JA, Shallberg L, Clark JT, Gullicksrud JA, DeLong JH, Douglas BB, Hart AP, Lanzar Z, O'Dea K, Konradt C, Park J, Kuchroo JR, Grubaugh D, Zaretsky AG, Brodsky IE, Malefyt RW, Christian DA, Sharpe AH, Hunter CA. Perry JA, et al. Nat Immunol. 2022 May;23(5):743-756. doi: 10.1038/s41590-022-01170-w. Epub 2022 Apr 18. Nat Immunol. 2022. PMID: 35437326 Free PMC article.
12 results