R01 CA193678/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2017	2
2018	1
2019	2
2020	4
2021	4
2024	0

1

Von Willebrand factor delays liver repair after acetaminophen-induced acute liver injury in mice.

Groeneveld D, Cline-Fedewa H, Baker KS, Williams KJ, Roth RA, Mittermeier K, Lisman T, Palumbo JS, Luyendyk JP. Groeneveld D, et al. J Hepatol. 2020 Jan;72(1):146-155. doi: 10.1016/j.jhep.2019.09.030. Epub 2019 Oct 10. J Hepatol. 2020. PMID: 31606553 Free PMC article.

2

Cell type-specific roles of PAR1 in Coxsackievirus B3 infection.

Bode MF, Schmedes CM, Egnatz GJ, Bharathi V, Hisada YM, Martinez D, Kawano T, Weithauser A, Rosenfeldt L, Rauch U, Palumbo JS, Antoniak S, Mackman N. Bode MF, et al. Sci Rep. 2021 Jul 12;11(1):14264. doi: 10.1038/s41598-021-93759-8. Sci Rep. 2021. PMID: 34253819 Free PMC article.

3

Fibrinogen activates focal adhesion kinase (FAK) promoting colorectal adenocarcinoma growth.

Sharma BK, Mureb D, Murab S, Rosenfeldt L, Francisco B, Cantrell R, Karns R, Romick-Rosendale L, Watanabe-Chailland M, Mast J, Flick MJ, Whitlock PW, Palumbo JS. Sharma BK, et al. J Thromb Haemost. 2021 Oct;19(10):2480-2494. doi: 10.1111/jth.15440. Epub 2021 Jul 19. J Thromb Haemost. 2021. PMID: 34192410 Free PMC article.

4

Thrombin promotes diet-induced obesity through fibrin-driven inflammation.

Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ. Kopec AK, et al. J Clin Invest. 2017 Aug 1;127(8):3152-3166. doi: 10.1172/JCI92744. Epub 2017 Jul 24. J Clin Invest. 2017. PMID: 28737512 Free PMC article.

5

Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis.

Boucher AA, Rosenfeldt L, Mureb D, Shafer J, Sharma BK, Lane A, Crowther RR, McKell MC, Whitt J, Alenghat T, Qualls J, Antoniak S, Mackman N, Flick MJ, Steinbrecher KA, Palumbo JS. Boucher AA, et al. J Thromb Haemost. 2020 Jan;18(1):91-103. doi: 10.1111/jth.14641. Epub 2019 Oct 11. J Thromb Haemost. 2020. PMID: 31539206 Free PMC article.

6

Protease-activated receptor-1 impedes prostate and intestinal tumor progression in mice.

Adams GN, Sharma BK, Rosenfeldt L, Frederick M, Flick MJ, Witte DP, Mosnier LO, Harmel-Laws E, Steinbrecher KA, Palumbo JS. Adams GN, et al. J Thromb Haemost. 2018 Nov;16(11):2258-2269. doi: 10.1111/jth.14277. Epub 2018 Sep 27. J Thromb Haemost. 2018. PMID: 30152921 Free PMC article.

7

Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice.

Shaw MA, Kombrinck KW, McElhinney KE, Sweet DR, Flick MJ, Palumbo JS, Cheng M, Esmon NL, Esmon CT, Brill A, Wagner DD, Degen JL, Mullins ES. Shaw MA, et al. Blood. 2016 Aug 4;128(5):721-31. doi: 10.1182/blood-2015-11-680280. Epub 2016 Jun 1. Blood. 2016. PMID: 27252233 Free PMC article.

8

PAR1 regulation of CXCL1 expression and neutrophil recruitment to the lung in mice infected with influenza A virus.

Antoniak S, Tatsumi K, Schmedes CM, Egnatz GJ, Auriemma AC, Bharathi V, Stokol T, Beck MA, Griffin JH, Palumbo JS, Mackman N. Antoniak S, et al. J Thromb Haemost. 2021 Apr;19(4):1103-1111. doi: 10.1111/jth.15221. Epub 2021 Feb 19. J Thromb Haemost. 2021. PMID: 33346953 Free PMC article.

9

Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.

Prasad JM, Negrón O, Du X, Mullins ES, Palumbo JS, Gilbertie JM, Höök M, Grover SP, Pawlinski R, Mackman N, Degen JL, Flick MJ. Prasad JM, et al. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2009837118. doi: 10.1073/pnas.2009837118. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2021. PMID: 33443167 Free PMC article.

10

Liver fibrosis is driven by protease-activated receptor-1 expressed by hepatic stellate cells in experimental chronic liver injury.

Poole LG, Pant A, Cline-Fedewa HM, Williams KJ, Copple BL, Palumbo JS, Luyendyk JP. Poole LG, et al. Res Pract Thromb Haemost. 2020 Jun 25;4(5):906-917. doi: 10.1002/rth2.12403. eCollection 2020 Jul. Res Pract Thromb Haemost. 2020. PMID: 32685902 Free PMC article.

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