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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2017 | 1 |
2018 | 1 |
2019 | 1 |
2020 | 2 |
2021 | 1 |
2022 | 2 |
2024 | 0 |
Search Results
7 results
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Page 1
Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes.
Elife. 2022 Jun 23;11:e72879. doi: 10.7554/eLife.72879.
Elife. 2022.
PMID: 35737447
Free PMC article.
Genome-scale CRISPR-Cas9 screen identifies druggable dependencies in TP53 wild-type Ewing sarcoma.
Stolte B, Iniguez AB, Dharia NV, Robichaud AL, Conway AS, Morgan AM, Alexe G, Schauer NJ, Liu X, Bird GH, Tsherniak A, Vazquez F, Buhrlage SJ, Walensky LD, Stegmaier K.
Stolte B, et al.
J Exp Med. 2018 Aug 6;215(8):2137-2155. doi: 10.1084/jem.20171066. Epub 2018 Jul 25.
J Exp Med. 2018.
PMID: 30045945
Free PMC article.
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Inhibition of the deubiquitinase USP10 induces degradation of SYK.
Yang J, Meng C, Weisberg E, Case A, Lamberto I, Magin RS, Adamia S, Wang J, Gray N, Liu S, Stone R, Sattler M, Buhrlage S, Griffin JD.
Yang J, et al.
Br J Cancer. 2020 Apr;122(8):1175-1184. doi: 10.1038/s41416-020-0731-z. Epub 2020 Feb 4.
Br J Cancer. 2020.
PMID: 32015510
Free PMC article.
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, Doench JG, Hahn WC, Buhrlage SJ, DeNicola GM, Kaelin WG Jr, Brugge JS.
Harris IS, et al.
Cell Metab. 2019 May 7;29(5):1166-1181.e6. doi: 10.1016/j.cmet.2019.01.020. Epub 2019 Feb 21.
Cell Metab. 2019.
PMID: 30799286
Free PMC article.
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Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2.
Yang J, Weisberg EL, Liu X, Magin RS, Chan WC, Hu B, Schauer NJ, Zhang S, Lamberto I, Doherty L, Meng C, Sattler M, Cabal-Hierro L, Winer E, Stone R, Marto JA, Griffin JD, Buhrlage SJ.
Yang J, et al.
Leukemia. 2022 Jan;36(1):210-220. doi: 10.1038/s41375-021-01336-9. Epub 2021 Jul 29.
Leukemia. 2022.
PMID: 34326465
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Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.
Lamberto I, Liu X, Seo HS, Schauer NJ, Iacob RE, Hu W, Das D, Mikhailova T, Weisberg EL, Engen JR, Anderson KC, Chauhan D, Dhe-Paganon S, Buhrlage SJ.
Lamberto I, et al.
Cell Chem Biol. 2017 Dec 21;24(12):1490-1500.e11. doi: 10.1016/j.chembiol.2017.09.003. Epub 2017 Oct 19.
Cell Chem Biol. 2017.
PMID: 29056421
Free PMC article.
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Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism.
Schauer NJ, Liu X, Magin RS, Doherty LM, Chan WC, Ficarro SB, Hu W, Roberts RM, Iacob RE, Stolte B, Giacomelli AO, Perera S, McKay K, Boswell SA, Weisberg EL, Ray A, Chauhan D, Dhe-Paganon S, Anderson KC, Griffin JD, Li J, Hahn WC, Sorger PK, Engen JR, Stegmaier K, Marto JA, Buhrlage SJ.
Schauer NJ, et al.
Sci Rep. 2020 Mar 24;10(1):5324. doi: 10.1038/s41598-020-62076-x.
Sci Rep. 2020.
PMID: 32210275
Free PMC article.
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