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Anticancer opportunities at every stage of chemokine function.
Ortiz Zacarías NV, Bemelmans MP, Handel TM, de Visser KE, Heitman LH. Ortiz Zacarías NV, et al. Trends Pharmacol Sci. 2021 Nov;42(11):912-928. doi: 10.1016/j.tips.2021.08.001. Epub 2021 Sep 11. Trends Pharmacol Sci. 2021. PMID: 34521537 Review.
Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.
Chen Q, Plasencia M, Li Z, Mukherjee S, Patra D, Chen CL, Klose T, Yao XQ, Kossiakoff AA, Chang L, Andrews PC, Tesmer JJG. Chen Q, et al. Nature. 2021 Jul;595(7868):600-605. doi: 10.1038/s41586-021-03721-x. Epub 2021 Jul 14. Nature. 2021. PMID: 34262173 Free PMC article.
Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors.
Gray AL, Karlsson R, Roberts ARE, Ridley AJL, Pun N, Khan B, Lawless C, Luís R, Szpakowska M, Chevigné A, Hughes CE, Medina-Ruiz L, Birchenough HL, Mulholland IZ, Salanga CL, Yates EA, Turnbull JE, Handel TM, Graham GJ, Jowitt TA, Schiessl I, Richter RP, Miller RL, Dyer DP. Gray AL, et al. Cell Rep. 2023 Jan 31;42(1):111930. doi: 10.1016/j.celrep.2022.111930. Epub 2023 Jan 5. Cell Rep. 2023. PMID: 36640356 Free PMC article.
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