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Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis.
Piper M, Hoen M, Darragh LB, Knitz MW, Nguyen D, Gadwa J, Durini G, Karakoc I, Grier A, Neupert B, Van Court B, Abdelazeem KNM, Yu J, Olimpo NA, Corbo S, Ross RB, Pham TT, Joshi M, Kedl RM, Saviola AJ, Amann M, Umaña P, Codarri Deak L, Klein C, D'Alessandro A, Karam SD. Piper M, et al. Cancer Cell. 2023 May 8;41(5):950-969.e6. doi: 10.1016/j.ccell.2023.04.001. Epub 2023 Apr 27. Cancer Cell. 2023. PMID: 37116489 Free PMC article.
Advances in the management of pancreatic cancer.
Del Chiaro M, Sugawara T, Karam SD, Messersmith WA. Del Chiaro M, et al. BMJ. 2023 Dec 13;383:e073995. doi: 10.1136/bmj-2022-073995. BMJ. 2023. PMID: 38164628 Review.
EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment.
Bhatia S, Nguyen D, Darragh LB, Van Court B, Sharma J, Knitz MW, Piper M, Bukkapatnam S, Gadwa J, Bickett TE, Bhuvane S, Corbo S, Wu B, Lee Y, Fujita M, Joshi M, Heasley LE, Ferris RL, Rodriguez O, Albanese C, Kapoor M, Pasquale EB, Karam SD. Bhatia S, et al. Nat Commun. 2022 Jun 20;13(1):3535. doi: 10.1038/s41467-022-31124-7. Nat Commun. 2022. PMID: 35725568 Free PMC article.
Targeting resistance to radiation-immunotherapy in cold HNSCCs by modulating the Treg-dendritic cell axis.
Knitz MW, Bickett TE, Darragh LB, Oweida AJ, Bhatia S, Van Court B, Bhuvane S, Piper M, Gadwa J, Mueller AC, Nguyen D, Nangia V, Osborne DG, Bai X, Ferrara SE, Boss MK, Goodspeed A, Burchill MA, Tamburini BAJ, Chan ED, Pickering CR, Clambey ET, Karam SD. Knitz MW, et al. J Immunother Cancer. 2021 Apr;9(4):e001955. doi: 10.1136/jitc-2020-001955. J Immunother Cancer. 2021. PMID: 33883256 Free PMC article.
A phase I/Ib trial and biological correlate analysis of neoadjuvant SBRT with single-dose durvalumab in HPV-unrelated locally advanced HNSCC.
Darragh LB, Knitz MM, Hu J, Clambey ET, Backus J, Dumit A, Samedi V, Bubak A, Greene C, Waxweiler T, Mehrotra S, Bhatia S, Gadwa J, Bickett T, Piper M, Fakhoury K, Liu A, Petit J, Bowles D, Thaker A, Atiyeh K, Goddard J, Hoyer R, Van Bokhoven A, Jordan K, Jimeno A, D'Alessandro A, Raben D, McDermott JD, Karam SD. Darragh LB, et al. Nat Cancer. 2022 Nov;3(11):1300-1317. doi: 10.1038/s43018-022-00450-6. Epub 2022 Nov 25. Nat Cancer. 2022. PMID: 36434392 Free PMC article. Clinical Trial.
37 results