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Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity.
Colbert JF, Kirsch JM, Erzen CL, Langouët-Astrié CJ, Thompson GE, McMurtry SA, Kofonow JM, Robertson CE, Kovacs EJ, Sullivan RC, Hippensteel JA, Sawant NV, De Nisco NJ, McCollister BD, Schwartz RS, Horswill AR, Frank DN, Duerkop BA, Schmidt EP. Colbert JF, et al. mBio. 2023 Jun 27;14(3):e0005223. doi: 10.1128/mbio.00052-23. Epub 2023 Apr 27. mBio. 2023. PMID: 37102874 Free PMC article.
Circulating heparan sulfate fragments mediate septic cognitive dysfunction.
Hippensteel JA, Anderson BJ, Orfila JE, McMurtry SA, Dietz RM, Su G, Ford JA, Oshima K, Yang Y, Zhang F, Han X, Yu Y, Liu J, Linhardt RJ, Meyer NJ, Herson PS, Schmidt EP. Hippensteel JA, et al. J Clin Invest. 2019 Apr 1;129(4):1779-1784. doi: 10.1172/JCI124485. Epub 2019 Mar 18. J Clin Invest. 2019. PMID: 30720464 Free PMC article.
New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021.
Martin TR, Zemans RL, Ware LB, Schmidt EP, Riches DWH, Bastarache L, Calfee CS, Desai TJ, Herold S, Hough CL, Looney MR, Matthay MA, Meyer N, Parikh SM, Stevens T, Thompson BT. Martin TR, et al. Am J Respir Cell Mol Biol. 2022 Sep;67(3):284-308. doi: 10.1165/rcmb.2022-0089WS. Am J Respir Cell Mol Biol. 2022. PMID: 35679511 Free PMC article.
Alveolar epithelial glycocalyx degradation mediates surfactant dysfunction and contributes to acute respiratory distress syndrome.
Rizzo AN, Haeger SM, Oshima K, Yang Y, Wallbank AM, Jin Y, Lettau M, McCaig LA, Wickersham NE, McNeil JB, Zakharevich I, McMurtry SA, Langouët-Astrié CJ, Kopf KW, Voelker DR, Hansen KC, Shaver CM, Kerchberger VE, Peterson RA, Kuebler WM, Ochs M, Veldhuizen RA, Smith BJ, Ware LB, Bastarache JA, Schmidt EP. Rizzo AN, et al. JCI Insight. 2022 Jan 25;7(2):e154573. doi: 10.1172/jci.insight.154573. JCI Insight. 2022. PMID: 34874923 Free PMC article.