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2020 1
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2023 2
2024 1

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Page 1
Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors.
Lv X, Lu X, Cao J, Luo Q, Ding Y, Peng F, Pataer A, Lu D, Han D, Malmberg E, Chan DW, Wang X, Savage SR, Mao S, Yu J, Peng F, Yan L, Meng H, Maneix L, Han Y, Chen Y, Yao W, Chang EC, Catic A, Lin X, Miles G, Huang P, Sun Z, Burt B, Wang H, Wang J, Yao QC, Zhang B, Roth JA, O'Malley BW, Ellis MJ, Rimawi MF, Ying H, Chen X. Lv X, et al. Science. 2023 Sep 8;381(6662):eabn4180. doi: 10.1126/science.abn4180. Epub 2023 Sep 8. Science. 2023. PMID: 37676964 Free PMC article.
Gene Environment Interactions in the Etiology of Neural Tube Defects.
Finnell RH, Caiaffa CD, Kim SE, Lei Y, Steele J, Cao X, Tukeman G, Lin YL, Cabrera RM, Wlodarczyk BJ. Finnell RH, et al. Front Genet. 2021 May 10;12:659612. doi: 10.3389/fgene.2021.659612. eCollection 2021. Front Genet. 2021. PMID: 34040637 Free PMC article. Review.
Actuation enhances patterning in human neural tube organoids.
Abdel Fattah AR, Daza B, Rustandi G, Berrocal-Rubio MÁ, Gorissen B, Poovathingal S, Davie K, Barrasa-Fano J, Cóndor M, Cao X, Rosenzweig DH, Lei Y, Finnell R, Verfaillie C, Sampaolesi M, Dedecker P, Van Oosterwyck H, Aerts S, Ranga A. Abdel Fattah AR, et al. Nat Commun. 2021 May 27;12(1):3192. doi: 10.1038/s41467-021-22952-0. Nat Commun. 2021. PMID: 34045434 Free PMC article.
Excess folic acid intake increases DNA de novo point mutations.
Cao X, Xu J, Lin YL, Cabrera RM, Chen Q, Zhang C, Steele JW, Han X, Gross SS, Wlodarczyk BJ, Lupski JR, Li W, Wang H, Finnell RH, Lei Y. Cao X, et al. Cell Discov. 2023 Feb 28;9(1):22. doi: 10.1038/s41421-022-00512-0. Cell Discov. 2023. PMID: 36849450 Free PMC article. No abstract available.
FKBP8 variants are risk factors for spina bifida.
Tian T, Cao X, Kim SE, Lin YL, Steele JW, Cabrera RM, Karki M, Yang W, Marini NJ, Hoffman EN, Han X, Hu C, Wang L, Wlodarczyk BJ, Shaw GM, Ren A, Finnell RH, Lei Y. Tian T, et al. Hum Mol Genet. 2020 Nov 4;29(18):3132-3144. doi: 10.1093/hmg/ddaa211. Hum Mol Genet. 2020. PMID: 32969478 Free PMC article.
CIC missense variants contribute to susceptibility for spina bifida.
Han X, Cao X, Aguiar-Pulido V, Yang W, Karki M, Ramirez PAP, Cabrera RM, Lin YL, Wlodarczyk BJ, Shaw GM, Ross ME, Zhang C, Finnell RH, Lei Y. Han X, et al. Hum Mutat. 2022 Dec;43(12):2021-2032. doi: 10.1002/humu.24460. Epub 2022 Sep 12. Hum Mutat. 2022. PMID: 36054333 Free PMC article.