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SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells.
Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ, Dong X, Wang M, Chen Z, Ho DD, Pitt GS, Schwartz RE, tenOever BR, Evans T, Chen S. Han Y, et al. Circ Res. 2022 Apr;130(7):963-977. doi: 10.1161/CIRCRESAHA.121.320518. Epub 2022 Mar 8. Circ Res. 2022. PMID: 35255712 Free PMC article.
Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response.
Papa A, Zakharov SI, Katchman AN, Kushner JS, Chen BX, Yang L, Liu G, Jimenez AS, Eisert RJ, Bradshaw GA, Dun W, Ali SR, Rodriques A, Zhou K, Topkara V, Yang M, Morrow JP, Tsai EJ, Karlin A, Wan E, Kalocsay M, Pitt GS, Colecraft HM, Ben-Johny M, Marx SO. Papa A, et al. Nat Cardiovasc Res. 2022 Nov;1(11):1022-1038. doi: 10.1038/s44161-022-00157-y. Epub 2022 Nov 14. Nat Cardiovasc Res. 2022. PMID: 36424916 Free PMC article.
Fibroblast growth factor homologous factors serve as a molecular rheostat in tuning arrhythmogenic cardiac late sodium current.
Chakouri N, Rivas S, Roybal D, Yang L, Diaz J, Hsu A, Mahling R, Chen BX, Owoyemi JO, DiSilvestre D, Sirabella D, Corneo B, Tomaselli GF, Dick IE, Marx SO, Ben-Johny M. Chakouri N, et al. Nat Cardiovasc Res. 2022 May;1(5):1-13. doi: 10.1038/s44161-022-00060-6. Epub 2022 May 16. Nat Cardiovasc Res. 2022. PMID: 35662881 Free PMC article.
Attenuating persistent sodium current-induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress.
Avula UMR, Dridi H, Chen BX, Yuan Q, Katchman AN, Reiken SR, Desai AD, Parsons S, Baksh H, Ma E, Dasrat P, Ji R, Lin Y, Sison C, Lederer WJ, Joca HC, Ward CW, Greiser M, Marks AR, Marx SO, Wan EY. Avula UMR, et al. JCI Insight. 2021 Oct 28;6(23):e147371. doi: 10.1172/jci.insight.147371. JCI Insight. 2021. PMID: 34710060 Free PMC article.
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D; NYSCF Global Stem Cell Array® Team; Paull D, Noggle SA, Xiang JZ, Studer L, Christini DJ, Pitt GS, Evans T, Chen S. Ghazizadeh Z, et al. iScience. 2022 Mar 25;25(4):104153. doi: 10.1016/j.isci.2022.104153. eCollection 2022 Apr 15. iScience. 2022. PMID: 35434558 Free PMC article.