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Recent developments in biased agonism.
Wisler JW, Xiao K, Thomsen AR, Lefkowitz RJ. Wisler JW, et al. Curr Opin Cell Biol. 2014 Apr;27:18-24. doi: 10.1016/j.ceb.2013.10.008. Epub 2013 Nov 20. Curr Opin Cell Biol. 2014. PMID: 24680426 Free PMC article. Review.
CaSR-mediated interactions between calcium and magnesium homeostasis in mice.
Quinn SJ, Thomsen AR, Egbuna O, Pang J, Baxi K, Goltzman D, Pollak M, Brown EM. Quinn SJ, et al. Am J Physiol Endocrinol Metab. 2013 Apr 1;304(7):E724-33. doi: 10.1152/ajpendo.00557.2012. Epub 2013 Jan 29. Am J Physiol Endocrinol Metab. 2013. PMID: 23360827 Free PMC article.
Biased agonism of the calcium-sensing receptor.
Thomsen AR, Hvidtfeldt M, Bräuner-Osborne H. Thomsen AR, et al. Cell Calcium. 2012 Feb;51(2):107-16. doi: 10.1016/j.ceca.2011.11.009. Epub 2011 Dec 20. Cell Calcium. 2012. PMID: 22192592
Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.
Liu CH, Gong Z, Liang ZL, Liu ZX, Yang F, Sun YJ, Ma ML, Wang YJ, Ji CR, Wang YH, Wang MJ, Cui FA, Lin A, Zheng WS, He DF, Qu CX, Xiao P, Liu CY, Thomsen AR, Joseph Cahill T 3rd, Kahsai AW, Yi F, Xiao KH, Xue T, Zhou Z, Yu X, Sun JP. Liu CH, et al. Nat Commun. 2017 Feb 9;8:14335. doi: 10.1038/ncomms14335. Nat Commun. 2017. PMID: 28181498 Free PMC article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
19 results