R37 CA065823/CA/NCI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2010	8
2011	7
2012	9
2013	8
2014	7
2015	3
2016	3
2017	2
2024	1

1

Kinase inhibitor therapy in CML: it's what's inside that counts.

Eide CA, Druker BJ, O'Hare T. Eide CA, et al. Oncotarget. 2013 Sep;4(9):1332-3. doi: 10.18632/oncotarget.1271. Oncotarget. 2013. PMID: 23934763 Free PMC article. No abstract available.

2

A requirement for SOCS-1 and SOCS-3 phosphorylation in Bcr-Abl-induced tumorigenesis.

Qiu X, Guo G, Chen K, Kashiwada M, Druker BJ, Rothman PB, Chen JL. Qiu X, et al. Neoplasia. 2012 Jun;14(6):547-58. doi: 10.1596/neo.12230. Neoplasia. 2012. PMID: 22787435 Free PMC article.

3

Ponatinib in refractory Philadelphia chromosome-positive leukemias.

Cortes JE, Kantarjian H, Shah NP, Bixby D, Mauro MJ, Flinn I, O'Hare T, Hu S, Narasimhan NI, Rivera VM, Clackson T, Turner CD, Haluska FG, Druker BJ, Deininger MW, Talpaz M. Cortes JE, et al. N Engl J Med. 2012 Nov 29;367(22):2075-88. doi: 10.1056/NEJMoa1205127. N Engl J Med. 2012. PMID: 23190221 Free PMC article. Clinical Trial.

4

Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting.

Jacob T, Agarwal A, Ramunno-Johnson D, O'Hare T, Gönen M, Tyner JW, Druker BJ, Vu TQ. Jacob T, et al. Sci Rep. 2016 Jun 20;6:28163. doi: 10.1038/srep28163. Sci Rep. 2016. PMID: 27320899 Free PMC article.

5

Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors.

Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K. Pietarinen PO, et al. Oncotarget. 2017 Apr 4;8(14):22606-22615. doi: 10.18632/oncotarget.15146. Oncotarget. 2017. PMID: 28186983 Free PMC article.

6

Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity Trial.

Guilhot F, Hughes TP, Cortes J, Druker BJ, Baccarani M, Gathmann I, Hayes M, Granvil C, Wang Y. Guilhot F, et al. Haematologica. 2012 May;97(5):731-8. doi: 10.3324/haematol.2011.045666. Epub 2012 Feb 7. Haematologica. 2012. PMID: 22315495 Free PMC article. Clinical Trial.

7

Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia.

Packer LM, Rana S, Hayward R, O'Hare T, Eide CA, Rebocho A, Heidorn S, Zabriskie MS, Niculescu-Duvaz I, Druker BJ, Springer C, Marais R. Packer LM, et al. Cancer Cell. 2011 Dec 13;20(6):715-27. doi: 10.1016/j.ccr.2011.11.004. Cancer Cell. 2011. PMID: 22169110 Free PMC article.

8

Alpha-synuclein regulates nucleolar DNA double-strand break repair in melanoma.

Arnold MR, Cohn GM, Oxe KC, Elliott SN, Moore C, Laraia PV, Shekoohi S, Brownell D, Meshul CK, Witt SN, Larsen DH, Unni VK. Arnold MR, et al. bioRxiv [Preprint]. 2024 Jan 14:2024.01.13.575526. doi: 10.1101/2024.01.13.575526. bioRxiv. 2024. PMID: 38260370 Free PMC article. Preprint.

9

A therapeutically targetable mechanism of BCR-ABL-independent imatinib resistance in chronic myeloid leukemia.

Ma L, Shan Y, Bai R, Xue L, Eide CA, Ou J, Zhu LJ, Hutchinson L, Cerny J, Khoury HJ, Sheng Z, Druker BJ, Li S, Green MR. Ma L, et al. Sci Transl Med. 2014 Sep 3;6(252):252ra121. doi: 10.1126/scitranslmed.3009073. Sci Transl Med. 2014. PMID: 25186176 Free PMC article.

10

Structural insight into selectivity and resistance profiles of ROS1 tyrosine kinase inhibitors.

Davare MA, Vellore NA, Wagner JP, Eide CA, Goodman JR, Drilon A, Deininger MW, O'Hare T, Druker BJ. Davare MA, et al. Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5381-90. doi: 10.1073/pnas.1515281112. Epub 2015 Sep 8. Proc Natl Acad Sci U S A. 2015. PMID: 26372962 Free PMC article.

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