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Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations.
Nat Biotechnol. 2010 Jun;28(6):595-9. doi: 10.1038/nbt.1641. Epub 2010 May 23.
Nat Biotechnol. 2010.
PMID: 20495550
Free PMC article.
Simultaneous detection of single molecules and singulated ensembles of molecules enables immunoassays with broad dynamic range.
Rissin DM, Fournier DR, Piech T, Kan CW, Campbell TG, Song L, Chang L, Rivnak AJ, Patel PP, Provuncher GK, Ferrell EP, Howes SC, Pink BA, Minnehan KA, Wilson DH, Duffy DC.
Rissin DM, et al.
Anal Chem. 2011 Mar 15;83(6):2279-85. doi: 10.1021/ac103161b. Epub 2011 Feb 23.
Anal Chem. 2011.
PMID: 21344864
Free PMC article.
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