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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gómez-Lechón MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Godoy P, et al. Arch Toxicol. 2013 Aug;87(8):1315-530. doi: 10.1007/s00204-013-1078-5. Epub 2013 Aug 23. Arch Toxicol. 2013. PMID: 23974980 Free PMC article. Review.
Sterile inflammation in acute liver injury: myth or mystery?
Woolbright BL, Jaeschke H. Woolbright BL, et al. Expert Rev Gastroenterol Hepatol. 2015;9(8):1027-9. doi: 10.1586/17474124.2015.1060855. Expert Rev Gastroenterol Hepatol. 2015. PMID: 26186639 Free PMC article. Review.
Oxidative Stress and Acute Hepatic Injury.
Ramachandran A, Jaeschke H. Ramachandran A, et al. Curr Opin Toxicol. 2018 Feb;7:17-21. doi: 10.1016/j.cotox.2017.10.011. Curr Opin Toxicol. 2018. PMID: 29399645 Free PMC article.
Caspase inhibitors for the treatment of liver disease: friend or foe?
Woolbright BL, Ding WX, Jaeschke H. Woolbright BL, et al. Expert Rev Gastroenterol Hepatol. 2017 May;11(5):397-399. doi: 10.1080/17474124.2017.1300060. Epub 2017 Mar 4. Expert Rev Gastroenterol Hepatol. 2017. PMID: 28276808 Free PMC article. No abstract available.
22 results