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Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43.
Jiang YX, Cao Q, Sawaya MR, Abskharon R, Ge P, DeTure M, Dickson DW, Fu JY, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Jiang YX, et al. Nature. 2022 May;605(7909):304-309. doi: 10.1038/s41586-022-04670-9. Epub 2022 Mar 28. Nature. 2022. PMID: 35344984 Free PMC article.
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE. Deniston CK, et al. Nature. 2020 Dec;588(7837):344-349. doi: 10.1038/s41586-020-2673-2. Epub 2020 Aug 19. Nature. 2020. PMID: 32814344 Free PMC article.
108 results