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Year | Number of Results |
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2016 | 1 |
2020 | 2 |
2021 | 2 |
2022 | 2 |
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Page 1
Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation.
Cell Stem Cell. 2022 Jan 6;29(1):11-35. doi: 10.1016/j.stem.2021.12.008.
Cell Stem Cell. 2022.
PMID: 34995492
Free PMC article.
Review.
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins.
Altman T, Ionescu A, Ibraheem A, Priesmann D, Gradus-Pery T, Farberov L, Alexandra G, Shelestovich N, Dafinca R, Shomron N, Rage F, Talbot K, Ward ME, Dori A, Krüger M, Perlson E.
Altman T, et al.
Nat Commun. 2021 Nov 25;12(1):6914. doi: 10.1038/s41467-021-27221-8.
Nat Commun. 2021.
PMID: 34824257
Free PMC article.
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Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
Prudencio M, Humphrey J, Pickles S, Brown AL, Hill SE, Kachergus JM, Shi J, Heckman MG, Spiegel MR, Cook C, Song Y, Yue M, Daughrity LM, Carlomagno Y, Jansen-West K, de Castro CF, DeTure M, Koga S, Wang YC, Sivakumar P, Bodo C, Candalija A, Talbot K, Selvaraj BT, Burr K, Chandran S, Newcombe J, Lashley T, Hubbard I, Catalano D, Kim D, Propp N, Fennessey S; NYGC ALS Consortium; Fagegaltier D, Phatnani H, Secrier M, Fisher EM, Oskarsson B, van Blitterswijk M, Rademakers R, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Josephs KA, Thompson EA, Raj T, Ward M, Dickson DW, Gendron TF, Fratta P, Petrucelli L.
Prudencio M, et al.
J Clin Invest. 2020 Nov 2;130(11):6080-6092. doi: 10.1172/JCI139741.
J Clin Invest. 2020.
PMID: 32790644
Free PMC article.
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Human iPSC co-culture model to investigate the interaction between microglia and motor neurons.
Vahsen BF, Gray E, Candalija A, Cramb KML, Scaber J, Dafinca R, Katsikoudi A, Xu Y, Farrimond L, Wade-Martins R, James WS, Turner MR, Cowley SA, Talbot K.
Vahsen BF, et al.
Sci Rep. 2022 Jul 23;12(1):12606. doi: 10.1038/s41598-022-16896-8.
Sci Rep. 2022.
PMID: 35871163
Free PMC article.
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The Role of Mitochondrial Dysfunction and ER Stress in TDP-43 and C9ORF72 ALS.
Dafinca R, Barbagallo P, Talbot K.
Dafinca R, et al.
Front Cell Neurosci. 2021 Apr 1;15:653688. doi: 10.3389/fncel.2021.653688. eCollection 2021.
Front Cell Neurosci. 2021.
PMID: 33867942
Free PMC article.
Review.
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C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
Dafinca R, Scaber J, Ababneh N, Lalic T, Weir G, Christian H, Vowles J, Douglas AG, Fletcher-Jones A, Browne C, Nakanishi M, Turner MR, Wade-Martins R, Cowley SA, Talbot K.
Dafinca R, et al.
Stem Cells. 2016 Aug;34(8):2063-78. doi: 10.1002/stem.2388. Epub 2016 May 4.
Stem Cells. 2016.
PMID: 27097283
Free PMC article.
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Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD.
Dafinca R, Barbagallo P, Farrimond L, Candalija A, Scaber J, Ababneh NA, Sathyaprakash C, Vowles J, Cowley SA, Talbot K.
Dafinca R, et al.
Stem Cell Reports. 2020 May 12;14(5):892-908. doi: 10.1016/j.stemcr.2020.03.023. Epub 2020 Apr 23.
Stem Cell Reports. 2020.
PMID: 32330447
Free PMC article.
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