Z01 HD001607/ImNIH/Intramural NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2015	1
2016	4
2019	4
2020	3
2021	2
2022	2
2023	3
2024	2

1

Inhibition of endolysosome fusion increases exosome secretion.

Shelke GV, Williamson CD, Jarnik M, Bonifacino JS. Shelke GV, et al. J Cell Biol. 2023 Jun 5;222(6):e202209084. doi: 10.1083/jcb.202209084. Epub 2023 May 22. J Cell Biol. 2023. PMID: 37213076 Free PMC article.

2

Intrathecal AAV9/AP4M1 gene therapy for hereditary spastic paraplegia 50 shows safety and efficacy in preclinical studies.

Chen X, Dong T, Hu Y, De Pace R, Mattera R, Eberhardt K, Ziegler M, Pirovolakis T, Sahin M, Bonifacino JS, Ebrahimi-Fakhari D, Gray SJ. Chen X, et al. J Clin Invest. 2023 May 15;133(10):e164575. doi: 10.1172/JCI164575. J Clin Invest. 2023. PMID: 36951961 Free PMC article.

3

Coatopathies: Genetic Disorders of Protein Coats.

Dell'Angelica EC, Bonifacino JS. Dell'Angelica EC, et al. Annu Rev Cell Dev Biol. 2019 Oct 6;35:131-168. doi: 10.1146/annurev-cellbio-100818-125234. Epub 2019 Aug 9. Annu Rev Cell Dev Biol. 2019. PMID: 31399000 Free PMC article. Review.

4

Biallelic BORCS8 variants cause an infantile-onset neurodegenerative disorder with altered lysosome dynamics.

De Pace R, Maroofian R, Paimboeuf A, Zamani M, Zaki MS, Sadeghian S, Azizimalamiri R, Galehdari H, Zeighami J, Williamson CD, Fleming E, Zhou D, Gannon JL, Thiffault I, Roze E, Suri M, Zifarelli G, Bauer P, Houlden H, Severino M, Patten SA, Farrow E, Bonifacino JS. De Pace R, et al. Brain. 2024 May 3;147(5):1751-1767. doi: 10.1093/brain/awad427. Brain. 2024. PMID: 38128568 Free PMC article.

5

Measurement of Lysosome Positioning by Shell Analysis and Line Scan.

Williamson CD, Guardia CM, De Pace R, Bonifacino JS, Saric A. Williamson CD, et al. Methods Mol Biol. 2022;2473:285-306. doi: 10.1007/978-1-0716-2209-4_19. Methods Mol Biol. 2022. PMID: 35819772 Free PMC article.

6

Lysosome Positioning Influences mTORC2 and AKT Signaling.

Jia R, Bonifacino JS. Jia R, et al. Mol Cell. 2019 Jul 11;75(1):26-38.e3. doi: 10.1016/j.molcel.2019.05.009. Epub 2019 May 23. Mol Cell. 2019. PMID: 31130364 Free PMC article.

7

RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin.

Keren-Kaplan T, Sarić A, Ghosh S, Williamson CD, Jia R, Li Y, Bonifacino JS. Keren-Kaplan T, et al. Nat Commun. 2022 Mar 21;13(1):1506. doi: 10.1038/s41467-022-28952-y. Nat Commun. 2022. PMID: 35314674 Free PMC article.

8

Phagocytosis: Phagolysosome vesiculation promotes cell corpse degradation.

De Pace R, Bonifacino JS. De Pace R, et al. Curr Biol. 2023 Feb 27;33(4):R143-R146. doi: 10.1016/j.cub.2023.01.017. Curr Biol. 2023. PMID: 36854271 Free PMC article.

9

TSSC1 is novel component of the endosomal retrieval machinery.

Gershlick DC, Schindler C, Chen Y, Bonifacino JS. Gershlick DC, et al. Mol Biol Cell. 2016 Sep 15;27(18):2867-78. doi: 10.1091/mbc.E16-04-0209. Epub 2016 Jul 20. Mol Biol Cell. 2016. PMID: 27440922 Free PMC article.

10

Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons.

De Pace R, Britt DJ, Mercurio J, Foster AM, Djavaherian L, Hoffmann V, Abebe D, Bonifacino JS. De Pace R, et al. Cell Rep. 2020 Jun 16;31(11):107775. doi: 10.1016/j.celrep.2020.107775. Cell Rep. 2020. PMID: 32553155 Free PMC article.

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