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Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability.
Brouwer PJM, Caniels TG, van der Straten K, Snitselaar JL, Aldon Y, Bangaru S, Torres JL, Okba NMA, Claireaux M, Kerster G, Bentlage AEH, van Haaren MM, Guerra D, Burger JA, Schermer EE, Verheul KD, van der Velde N, van der Kooi A, van Schooten J, van Breemen MJ, Bijl TPL, Sliepen K, Aartse A, Derking R, Bontjer I, Kootstra NA, Wiersinga WJ, Vidarsson G, Haagmans BL, Ward AB, de Bree GJ, Sanders RW, van Gils MJ. Brouwer PJM, et al. Among authors: aartse a. Science. 2020 Aug 7;369(6504):643-650. doi: 10.1126/science.abc5902. Epub 2020 Jun 15. Science. 2020. PMID: 32540902 Free PMC article.
Decreased Passive Immunity to Respiratory Viruses through Human Milk during the COVID-19 Pandemic.
Grobben M, Juncker HG, van der Straten K, Lavell AHA, Schinkel M, Buis DTP, Wilbrink MF, Tejjani K, Claireaux MAF, Aartse A, de Groot CJM, Pajkrt D, Bomers MK, Sikkens JJ, van Gils MJ, van Goudoever JB, van Keulen BJ. Grobben M, et al. Among authors: aartse a. Microbiol Spectr. 2022 Aug 31;10(4):e0040522. doi: 10.1128/spectrum.00405-22. Epub 2022 Jun 28. Microbiol Spectr. 2022. PMID: 35762813 Free PMC article.
A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike.
Claireaux M, Caniels TG, de Gast M, Han J, Guerra D, Kerster G, van Schaik BDC, Jongejan A, Schriek AI, Grobben M, Brouwer PJM, van der Straten K, Aldon Y, Capella-Pujol J, Snitselaar JL, Olijhoek W, Aartse A, Brinkkemper M, Bontjer I, Burger JA, Poniman M, Bijl TPL, Torres JL, Copps J, Martin IC, de Taeye SW, de Bree GJ, Ward AB, Sliepen K, van Kampen AHC, Moerland PD, Sanders RW, van Gils MJ. Claireaux M, et al. Among authors: aartse a. Nat Commun. 2022 Aug 4;13(1):4539. doi: 10.1038/s41467-022-32232-0. Nat Commun. 2022. PMID: 35927266 Free PMC article.
Primary antibody response after influenza virus infection is first dominated by low-mutated HA-stem antibodies followed by higher-mutated HA-head antibodies.
Aartse A, Mortier D, Mooij P, Hofman S, van Haaren MM, Corcoran M, Karlsson Hedestam GB, Eggink D, Claireaux M, Bogers WMJM, van Gils MJ, Koopman G. Aartse A, et al. Front Immunol. 2022 Nov 3;13:1026951. doi: 10.3389/fimmu.2022.1026951. eCollection 2022. Front Immunol. 2022. PMID: 36405682 Free PMC article.
Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates.
Reiss EIMM, van Haaren MM, van Schooten J, Claireaux MAF, Maisonnasse P, Antanasijevic A, Allen JD, Bontjer I, Torres JL, Lee WH, Ozorowski G, Vázquez Bernat N, Kaduk M, Aldon Y, Burger JA, Chawla H, Aartse A, Tolazzi M, Gao H, Mundsperger P, Crispin M, Montefiori DC, Karlsson Hedestam GB, Scarlatti G, Ward AB, Le Grand R, Shattock R, Dereuddre-Bosquet N, Sanders RW, van Gils MJ. Reiss EIMM, et al. Among authors: aartse a. NPJ Vaccines. 2022 Nov 25;7(1):152. doi: 10.1038/s41541-022-00576-9. NPJ Vaccines. 2022. PMID: 36433972 Free PMC article.
Vaccine-induced neutralizing antibody responses to seasonal influenza virus H1N1 strains are not enhanced during subsequent pandemic H1N1 infection.
Mooij P, Mortier D, Aartse A, Murad AB, Correia R, Roldão A, Alves PM, Fagrouch Z, Eggink D, Stockhofe N, Engelhardt OG, Verschoor EJ, van Gils MJ, Bogers WM, Carrondo MJT, Remarque EJ, Koopman G. Mooij P, et al. Among authors: aartse a. Front Immunol. 2023 Aug 24;14:1256094. doi: 10.3389/fimmu.2023.1256094. eCollection 2023. Front Immunol. 2023. PMID: 37691927 Free PMC article.
Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines.
Del Moral-Sánchez I, Wee EG, Xian Y, Lee WH, Allen JD, Torrents de la Peña A, Fróes Rocha R, Ferguson J, León AN, Koekkoek S, Schermer EE, Burger JA, Kumar S, Zwolsman R, Brinkkemper M, Aartse A, Eggink D, Han J, Yuan M, Crispin M, Ozorowski G, Ward AB, Wilson IA, Hanke T, Sliepen K, Sanders RW. Del Moral-Sánchez I, et al. Among authors: aartse a. NPJ Vaccines. 2024 Apr 6;9(1):74. doi: 10.1038/s41541-024-00862-8. NPJ Vaccines. 2024. PMID: 38582771 Free PMC article.
13 results