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Antisense oligonucleotides increase Scn1a expression and reduce seizures and SUDEP incidence in a mouse model of Dravet syndrome.
Sci Transl Med. 2020 Aug 26;12(558):eaaz6100. doi: 10.1126/scitranslmed.aaz6100.
Sci Transl Med. 2020.
PMID: 32848094
Excitatory and inhibitory neuron defects in a mouse model of Scn1b-linked EIEE52.
Hull JM, O'Malley HA, Chen C, Yuan Y, Denomme N, Bouza AA, Anumonwo C, Lopez-Santiago LF, Isom LL.
Hull JM, et al. Among authors: anumonwo c.
Ann Clin Transl Neurol. 2020 Nov;7(11):2137-2149. doi: 10.1002/acn3.51205. Epub 2020 Sep 26.
Ann Clin Transl Neurol. 2020.
PMID: 32979291
Free PMC article.
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Mapt deletion fails to rescue premature lethality in two models of sodium channel epilepsy.
Chen C, Holth JK, Bunton-Stasyshyn R, Anumonwo CK, Meisler MH, Noebels JL, Isom LL.
Chen C, et al. Among authors: anumonwo ck.
Ann Clin Transl Neurol. 2018 Jul 5;5(8):982-987. doi: 10.1002/acn3.599. eCollection 2018 Aug.
Ann Clin Transl Neurol. 2018.
PMID: 30128323
Free PMC article.
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