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Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.
Clarke M, Mackay A, Ismer B, Pickles JC, Tatevossian RG, Newman S, Bale TA, Stoler I, Izquierdo E, Temelso S, Carvalho DM, Molinari V, Burford A, Howell L, Virasami A, Fairchild AR, Avery A, Chalker J, Kristiansen M, Haupfear K, Dalton JD, Orisme W, Wen J, Hubank M, Kurian KM, Rowe C, Maybury M, Crosier S, Knipstein J, Schüller U, Kordes U, Kram DE, Snuderl M, Bridges L, Martin AJ, Doey LJ, Al-Sarraj S, Chandler C, Zebian B, Cairns C, Natrajan R, Boult JKR, Robinson SP, Sill M, Dunkel IJ, Gilheeney SW, Rosenblum MK, Hughes D, Proszek PZ, Macdonald TJ, Preusser M, Haberler C, Slavc I, Packer R, Ng HK, Caspi S, Popović M, Faganel Kotnik B, Wood MD, Baird L, Davare MA, Solomon DA, Olsen TK, Brandal P, Farrell M, Cryan JB, Capra M, Karremann M, Schittenhelm J, Schuhmann MU, Ebinger M, Dinjens WNM, Kerl K, Hettmer S, Pietsch T, Andreiuolo F, Driever PH, Korshunov A, Hiddingh L, Worst BC, Sturm D, Zuckermann M, Witt O, Bloom T, Mitchell C, Miele E, Colafati GS, Diomedi-Camassei F, Bailey S, Moore AS, Hassall TEG, Lowis SP, Tsoli M, Cowley MJ, Ziegler DS, Karajannis MA, Aquilina K, Hargrave DR, Carceller F, Marshall LV, von Deimling A, Kramm CM, Pfister SM, Sahm F, Baker SJ, Mastr… See abstract for full author list ➔ Clarke M, et al. Among authors: aquilina k. Cancer Discov. 2020 Jul;10(7):942-963. doi: 10.1158/2159-8290.CD-19-1030. Epub 2020 Apr 1. Cancer Discov. 2020. PMID: 32238360 Free PMC article.
Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.
Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP. Apps JR, et al. Among authors: aquilina k. Acta Neuropathol. 2018 May;135(5):757-777. doi: 10.1007/s00401-018-1830-2. Epub 2018 Mar 14. Acta Neuropathol. 2018. PMID: 29541918 Free PMC article.
The utility of brain biopsy in pediatric cryptogenic neurological disease.
Layard Horsfall H, Toescu SM, Grover PJ, Hassell J, Sayer C, Hemingway C, Harding B, Jacques TS, Aquilina K. Layard Horsfall H, et al. Among authors: aquilina k. J Neurosurg Pediatr. 2020 Jul 3;26(4):431-438. doi: 10.3171/2020.4.PEDS19783. J Neurosurg Pediatr. 2020. PMID: 32619987
Spectrum of neuroimaging findings post-proton beam therapy in a large pediatric cohort.
Bhattacharya D, Chhabda S, Lakshmanan R, Tan R, Warne R, Benenati M, Michalski A, Aquilina K, Jacques T, Hargrave D, Chang YC, Gains J, Mankad K. Bhattacharya D, et al. Among authors: aquilina k. Childs Nerv Syst. 2021 Feb;37(2):435-446. doi: 10.1007/s00381-020-04819-9. Epub 2020 Jul 23. Childs Nerv Syst. 2021. PMID: 32705327
Neurosurgical experience of managing optic pathway gliomas.
Hill CS, Khan M, Phipps K, Green K, Hargrave D, Aquilina K. Hill CS, et al. Among authors: aquilina k. Childs Nerv Syst. 2021 Jun;37(6):1917-1929. doi: 10.1007/s00381-021-05060-8. Epub 2021 Feb 3. Childs Nerv Syst. 2021. PMID: 33532921 Free PMC article. Review.
138 results