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Anti-tumor activity of selective inhibitor of nuclear export (SINE) compounds, is enhanced in non-Hodgkin lymphoma through combination with mTOR inhibitor and dexamethasone.
Muqbil I, Aboukameel A, Elloul S, Carlson R, Senapedis W, Baloglu E, Kauffman M, Shacham S, Bhutani D, Zonder J, Azmi AS, Mohammad RM. Muqbil I, et al. Among authors: azmi as. Cancer Lett. 2016 Dec 28;383(2):309-317. doi: 10.1016/j.canlet.2016.09.016. Epub 2016 Sep 28. Cancer Lett. 2016. PMID: 27693556 Free PMC article.
Selinexor, a Selective Inhibitor of Nuclear Export (SINE) compound, acts through NF-κB deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death.
Kashyap T, Argueta C, Aboukameel A, Unger TJ, Klebanov B, Mohammad RM, Muqbil I, Azmi AS, Drolen C, Senapedis W, Lee M, Kauffman M, Shacham S, Landesman Y. Kashyap T, et al. Among authors: azmi as. Oncotarget. 2016 Nov 29;7(48):78883-78895. doi: 10.18632/oncotarget.12428. Oncotarget. 2016. PMID: 27713151 Free PMC article.
Targeting Cancer at the Nuclear Pore.
Azmi AS, Mohammad RM. Azmi AS, et al. J Clin Oncol. 2016 Dec;34(34):4180-4182. doi: 10.1200/JCO.2016.67.5637. Epub 2016 Oct 23. J Clin Oncol. 2016. PMID: 27863200 No abstract available.
Nuclear Export Inhibition for Pancreatic Cancer Therapy.
Muqbil I, Azmi AS, Mohammad RM. Muqbil I, et al. Among authors: azmi as. Cancers (Basel). 2018 May 7;10(5):138. doi: 10.3390/cancers10050138. Cancers (Basel). 2018. PMID: 29735942 Free PMC article. Review.
188 results