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Regulated genes in psoriatic skin during treatment with fumaric acid esters.
Onderdijk AJ, Balak DM, Baerveldt EM, Florencia EF, Kant M, Laman JD, van IJcken WF, Racz E, de Ridder D, Thio HB, Prens EP. Onderdijk AJ, et al. Among authors: balak dm. Br J Dermatol. 2014 Oct;171(4):732-41. doi: 10.1111/bjd.13128. Epub 2014 Sep 30. Br J Dermatol. 2014. PMID: 24852654
IMO-8400, a toll-like receptor 7, 8, and 9 antagonist, demonstrates clinical activity in a phase 2a, randomized, placebo-controlled trial in patients with moderate-to-severe plaque psoriasis.
Balak DM, van Doorn MB, Arbeit RD, Rijneveld R, Klaassen E, Sullivan T, Brevard J, Thio HB, Prens EP, Burggraaf J, Rissmann R. Balak DM, et al. Clin Immunol. 2017 Jan;174:63-72. doi: 10.1016/j.clim.2016.09.015. Epub 2016 Nov 20. Clin Immunol. 2017. PMID: 27876460 Clinical Trial.
62 results