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Thalidomide-derived immunomodulatory drugs as therapeutic agents.
Galustian C, Labarthe MC, Bartlett JB, Dalgleish AG. Galustian C, et al. Among authors: bartlett jb. Expert Opin Biol Ther. 2004 Dec;4(12):1963-70. doi: 10.1517/14712598.4.12.1963. Expert Opin Biol Ther. 2004. PMID: 15571458 Review.
Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers.
Bartlett JB, Michael A, Clarke IA, Dredge K, Nicholson S, Kristeleit H, Polychronis A, Pandha H, Muller GW, Stirling DI, Zeldis J, Dalgleish AG. Bartlett JB, et al. Br J Cancer. 2004 Mar 8;90(5):955-61. doi: 10.1038/sj.bjc.6601579. Br J Cancer. 2004. PMID: 14997189 Free PMC article. Clinical Trial.
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.
Galustian C, Meyer B, Labarthe MC, Dredge K, Klaschka D, Henry J, Todryk S, Chen R, Muller G, Stirling D, Schafer P, Bartlett JB, Dalgleish AG. Galustian C, et al. Among authors: bartlett jb. Cancer Immunol Immunother. 2009 Jul;58(7):1033-45. doi: 10.1007/s00262-008-0620-4. Epub 2008 Nov 14. Cancer Immunol Immunother. 2009. PMID: 19009291 Free PMC article.
28 results