Berkers CR - Search Results

1

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.

Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. Verdoes M, et al. Among authors: berkers cr. Chem Biol. 2006 Nov;13(11):1217-26. doi: 10.1016/j.chembiol.2006.09.013. Chem Biol. 2006. PMID: 17114003

2

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib.

Berkers CR, Verdoes M, Lichtman E, Fiebiger E, Kessler BM, Anderson KC, Ploegh HL, Ovaa H, Galardy PJ. Berkers CR, et al. Nat Methods. 2005 May;2(5):357-62. doi: 10.1038/nmeth759. Epub 2005 Apr 21. Nat Methods. 2005. PMID: 15846363

3

Immunotherapeutic potential for ceramide-based activators of iNKT cells.

Berkers CR, Ovaa H. Berkers CR, et al. Trends Pharmacol Sci. 2005 May;26(5):252-7. doi: 10.1016/j.tips.2005.03.005. Trends Pharmacol Sci. 2005. PMID: 15860372 Review.

4

A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib.

Chauhan D, Catley L, Li G, Podar K, Hideshima T, Velankar M, Mitsiades C, Mitsiades N, Yasui H, Letai A, Ovaa H, Berkers C, Nicholson B, Chao TH, Neuteboom ST, Richardson P, Palladino MA, Anderson KC. Chauhan D, et al. Cancer Cell. 2005 Nov;8(5):407-19. doi: 10.1016/j.ccr.2005.10.013. Cancer Cell. 2005. PMID: 16286248 Free article.

5

Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome.

Groll M, Berkers CR, Ploegh HL, Ovaa H. Groll M, et al. Among authors: berkers cr. Structure. 2006 Mar;14(3):451-6. doi: 10.1016/j.str.2005.11.019. Structure. 2006. PMID: 16531229 Free article.

6

Chemical proteomics profiling of proteasome activity.

Verdoes M, Berkers CR, Florea BI, van Swieten PF, Overkleeft HS, Ovaa H. Verdoes M, et al. Among authors: berkers cr. Methods Mol Biol. 2006;328:51-69. doi: 10.1385/1-59745-026-X:51. Methods Mol Biol. 2006. PMID: 16785641

7

Activity patterns of proteasome subunits reflect bortezomib sensitivity of hematologic malignancies and are variable in primary human leukemia cells.

Kraus M, Rückrich T, Reich M, Gogel J, Beck A, Kammer W, Berkers CR, Burg D, Overkleeft H, Ovaa H, Driessen C. Kraus M, et al. Among authors: berkers cr. Leukemia. 2007 Jan;21(1):84-92. doi: 10.1038/sj.leu.2404414. Epub 2006 Oct 5. Leukemia. 2007. PMID: 17024115

8

Profiling proteasome activity in tissue with fluorescent probes.

Berkers CR, van Leeuwen FW, Groothuis TA, Peperzak V, van Tilburg EW, Borst J, Neefjes JJ, Ovaa H. Berkers CR, et al. Mol Pharm. 2007 Sep-Oct;4(5):739-48. doi: 10.1021/mp0700256. Epub 2007 Aug 21. Mol Pharm. 2007. PMID: 17708652

9

Automated online sequential isotope labeling for protein quantitation applied to proteasome tissue-specific diversity.

Raijmakers R, Berkers CR, de Jong A, Ovaa H, Heck AJ, Mohammed S. Raijmakers R, et al. Among authors: berkers cr. Mol Cell Proteomics. 2008 Sep;7(9):1755-62. doi: 10.1074/mcp.M800093-MCP200. Epub 2008 Jun 4. Mol Cell Proteomics. 2008. PMID: 18534969 Free PMC article.

10

Transpeptidation and reverse proteolysis and their consequences for immunity.

Berkers CR, de Jong A, Ovaa H, Rodenko B. Berkers CR, et al. Int J Biochem Cell Biol. 2009 Jan;41(1):66-71. doi: 10.1016/j.biocel.2008.08.036. Epub 2008 Sep 4. Int J Biochem Cell Biol. 2009. PMID: 18817889 Review.

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