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CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner.
Abdelouahab H, Zhang Y, Wittner M, Oishi S, Fujii N, Besancenot R, Plo I, Ribrag V, Solary E, Vainchenker W, Barosi G, Louache F. Abdelouahab H, et al. Among authors: besancenot r. Oncotarget. 2016 Jul 22;8(33):54082-54095. doi: 10.18632/oncotarget.10789. eCollection 2017 Aug 15. Oncotarget. 2016. PMID: 28903325 Free PMC article.
Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis.
Chaligné R, James C, Tonetti C, Besancenot R, Le Couédic JP, Fava F, Mazurier F, Godin I, Maloum K, Larbret F, Lécluse Y, Vainchenker W, Giraudier S. Chaligné R, et al. Among authors: besancenot r. Blood. 2007 Nov 15;110(10):3735-43. doi: 10.1182/blood-2007-05-089003. Epub 2007 Aug 20. Blood. 2007. PMID: 17709604 Free article.
Thrombopoietin receptor down-modulation by JAK2 V617F: restoration of receptor levels by inhibitors of pathologic JAK2 signaling and of proteasomes.
Pecquet C, Diaconu CC, Staerk J, Girardot M, Marty C, Royer Y, Defour JP, Dusa A, Besancenot R, Giraudier S, Villeval JL, Knoops L, Courtoy PJ, Vainchenker W, Constantinescu SN. Pecquet C, et al. Among authors: besancenot r. Blood. 2012 May 17;119(20):4625-35. doi: 10.1182/blood-2011-08-372524. Epub 2012 Feb 29. Blood. 2012. PMID: 22378845 Free article.