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Lipoprotein lipase is active as a monomer.
Beigneux AP, Allan CM, Sandoval NP, Cho GW, Heizer PJ, Jung RS, Stanhope KL, Havel PJ, Birrane G, Meiyappan M, Gill JE 4th, Murakami M, Miyashita K, Nakajima K, Ploug M, Fong LG, Young SG. Beigneux AP, et al. Among authors: birrane g. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6319-6328. doi: 10.1073/pnas.1900983116. Epub 2019 Mar 8. Proc Natl Acad Sci U S A. 2019. PMID: 30850549 Free PMC article.
The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing.
Song W, Beigneux AP, Weston TA, Chen K, Yang Y, Nguyen LP, Guagliardo P, Jung H, Tran AP, Tu Y, Tran C, Birrane G, Miyashita K, Nakajima K, Murakami M, Tontonoz P, Jiang H, Ploug M, Fong LG, Young SG. Song W, et al. Among authors: birrane g. Proc Natl Acad Sci U S A. 2023 Oct 31;120(44):e2313825120. doi: 10.1073/pnas.2313825120. Epub 2023 Oct 23. Proc Natl Acad Sci U S A. 2023. PMID: 37871217 Free PMC article.
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity.
Chen YQ, Yang Y, Zhen EY, Beyer TP, Li H, Wen Y, Ehsani M, Jackson N, Xie K, Jung H, Scheithauer JL, Kumari A, Birrane G, Russell AM, Balasubramaniam D, Liao Z, Siegel RW, Qian Y, Ploug M, Young SG, Konrad RJ. Chen YQ, et al. Among authors: birrane g. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2322332121. doi: 10.1073/pnas.2322332121. Epub 2024 Apr 16. Proc Natl Acad Sci U S A. 2024. PMID: 38625948
48 results