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Investigation of the influence of CYP1A2 and CYP2C19 genetic polymorphism on 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide (A77 1726) pharmacokinetics in leflunomide-treated patients with rheumatoid arthritis.
Bohanec Grabar P, Grabnar I, Rozman B, Logar D, Tomsic M, Suput D, Trdan T, Peterlin Masic L, Mrhar A, Dolzan V. Bohanec Grabar P, et al. Drug Metab Dispos. 2009 Oct;37(10):2061-8. doi: 10.1124/dmd.109.027482. Epub 2009 Jul 6. Drug Metab Dispos. 2009. PMID: 19581389