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Vectorization in an oncolytic vaccinia virus of an antibody, a Fab and a scFv against programmed cell death -1 (PD-1) allows their intratumoral delivery and an improved tumor-growth inhibition.
Oncoimmunology. 2016 Sep 9;5(10):e1220467. doi: 10.1080/2162402X.2016.1220467. eCollection 2016.
Oncoimmunology. 2016.
PMID: 27853644
Free PMC article.
Yeast virus-derived stimulator of the innate immune system augments the efficacy of virus vector-based immunotherapy.
Claudepierre MC, Hortelano J, Schaedler E, Kleinpeter P, Geist M, Remy-Ziller C, Brandely R, Tosch C, Laruelle L, Jawhari A, Menguy T, Marchand JB, Romby P, Schultz P, Hartmann G, Rooke R, Bonnefoy JY, Preville X, Rittner K.
Claudepierre MC, et al. Among authors: brandely r.
J Virol. 2014 May;88(10):5242-55. doi: 10.1128/JVI.03819-13. Epub 2014 Feb 26.
J Virol. 2014.
PMID: 24574403
Free PMC article.
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TG1050, an immunotherapeutic to treat chronic hepatitis B, induces robust T cells and exerts an antiviral effect in HBV-persistent mice.
Martin P, Dubois C, Jacquier E, Dion S, Mancini-Bourgine M, Godon O, Kratzer R, Lelu-Santolaria K, Evlachev A, Meritet JF, Schlesinger Y, Villeval D, Strub JM, Van Dorsselaer A, Marchand JB, Geist M, Brandely R, Findeli A, Boukhebza H, Menguy T, Silvestre N, Michel ML, Inchauspé G.
Martin P, et al. Among authors: brandely r.
Gut. 2015 Dec;64(12):1961-71. doi: 10.1136/gutjnl-2014-308041. Epub 2014 Nov 26.
Gut. 2015.
PMID: 25429051
Free PMC article.
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Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators.
Gallardo F, Schmitt D, Brandely R, Brua C, Silvestre N, Findeli A, Foloppe J, Top S, Kappler-Gratias S, Quentin-Froignant C, Morin R, Lagarde JM, Bystricky K, Bertagnoli S, Erbs P.
Gallardo F, et al. Among authors: brandely r.
Biomedicines. 2020 Nov 26;8(12):543. doi: 10.3390/biomedicines8120543.
Biomedicines. 2020.
PMID: 33256205
Free PMC article.
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Viral Delivery of IL-7 Is a Potent Immunotherapy Stimulating Innate and Adaptive Immunity and Confers Survival in Sepsis Models.
Lélu K, Dubois C, Evlachev A, Crausaz M, Baldazza M, Kehrer N, Brandely R, Schlesinger Y, Silvestre N, Marchand JB, Bastien B, Leung-Theung-Long S, Unsinger J, Martin P, Inchauspé G.
Lélu K, et al. Among authors: brandely r.
J Immunol. 2022 Jul 1;209(1):99-117. doi: 10.4049/jimmunol.2101145. Epub 2022 Jun 6.
J Immunol. 2022.
PMID: 35667841
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Design and selection of anti-PD-L1 single-domain antibody and tumor necrosis factor superfamily ligands for an optimal vectorization in an oncolytic virus.
Remy C, Pintado E, Dunlop M, Schön S, Kleinpeter P, Rozanes H, Fend L, Brandely R, Geist M, Suhner D, Winter E, Silvestre N, Huguet C, Fitzgerald P, Quéméneur E, Marchand JB.
Remy C, et al. Among authors: brandely r.
Front Bioeng Biotechnol. 2023 Nov 15;11:1247802. doi: 10.3389/fbioe.2023.1247802. eCollection 2023.
Front Bioeng Biotechnol. 2023.
PMID: 38053848
Free PMC article.
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HIV-1 core proteins expressed from recombinant vaccinia viruses.
Rautmann G, Kieny MP, Brandely R, Dott K, Girard M, Montagnier L, Lecocq JP.
Rautmann G, et al. Among authors: brandely r.
AIDS Res Hum Retroviruses. 1989 Apr;5(2):147-57. doi: 10.1089/aid.1989.5.147.
AIDS Res Hum Retroviruses. 1989.
PMID: 2713165
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